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multicrispr

Bioc current

Multi-locus multi-purpose Crispr/Cas design

v1.22.0 · software · GPL-2

Release Lineage

Entered 3.12 · Oct 28, 2020

Current · Requires R 4.6

1.0 In 12 of 49 releases 3.23

Description

This package is for designing Crispr/Cas9 and Prime Editing experiments. It contains functions to (1) define and transform genomic targets, (2) find spacers (4) count offtarget (mis)matches, and (5) compute Doench2016/2014 targeting efficiency. Care has been taken for multicrispr to scale well towards large target sets, enabling the design of large Crispr/Cas9 libraries.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

163 29 exported

Complexity

2.4 avg / 10 max

Call network

163 nodes / 364 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

5,492

Files

276

Compiled share

0%

Has compiled src

No

Language breakdown

R 3,744 (68.2%)Tests 88 (1.6%)Docs 1,255 (22.9%)Vignettes 405 (7.4%)

API

Exported functions

29

Internal functions

56

Testing & CI

Has tests

Yes

Test-to-code ratio

0.02

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.0

System requirements

C++ standard

License

GPL-2

License flags

SPDX valid, OSI approved

History

Versions

12

First release

2020-10-27

Latest release

2026-04-28

Avg cadence

197 days

Cold removal rate

Dep drift

3

LOC over versions

v3.12: 4,613 LOCv3.13: 4,613 LOCv3.14: 4,622 LOCv3.15: 4,622 LOCv3.16: 4,622 LOCv3.17: 4,622 LOCv3.18: 5,489 LOCv3.19: 5,489 LOCv3.20: 5,489 LOCv3.21: 5,489 LOCv3.22: 5,492 LOCv3.23: 5,492 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 40 wordsVignettesYes · dynamicpkgdown siteYesNEWSYes · 67% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
97%
Return-value docs
100%
References docs
4%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("multicrispr")
Bhagwat, A., Bentsen, M., Graumann, J., Lawrence, M., Looso, M., Pagès, H., Preussner, J., Wiegandt, R., & ´Cotton, R. (2026). multicrispr: Multi-locus multi-purpose Crispr/Cas design (Version 1.22.0) [Computer software]. https://bioconductor.org/packages/multicrispr

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for multicrispr version 1.22.0 [Data set]. HJJB, LLC. Data release v2026-08-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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