GenoGAM
Bioc removedA GAM based framework for analysis of ChIP-Seq data
Release Lineage
Entered 3.3 · May 4, 2016
Removed after 3.15 · Apr 27, 2022
Description
This package allows statistical analysis of genome-wide data with smooth functions using generalized additive models based on the implementation from the R-package 'mgcv'. It provides methods for the statistical analysis of ChIP-Seq data including inference of protein occupancy, and pointwise and region-wise differential analysis. Estimation of dispersion and smoothing parameters is performed by cross-validation. Scaling of generalized additive model fitting to whole chromosomes is achieved by parallelization over overlapping genomic intervals.
None published for Bioconductor
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People
- Georg Stricker author maintainer
- Alexander Engelhardt author
- Julien Gagneur author
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