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CleanUpRNAseq

Bioc current

Detect and Correct Genomic DNA Contamination in RNA-seq Data

v1.6.0 · Package record · software · GPL-3

Release Lineage

Entered 3.20 · Oct 30, 2024

Current · Requires R 4.6

1.0 In 4 of 49 releases 3.23

Description

RNA-seq data generated by some library preparation methods, such as rRNA-depletion-based method and the SMART-seq method, might be contaminated by genomic DNA (gDNA), if DNase I disgestion is not performed properly during RNA preparation. CleanUpRNAseq is developed to check if RNA-seq data is suffered from gDNA contamination. If so, it can perform correction for gDNA contamination and reduce false discovery rate of differentially expressed genes.

Advisories

None published for Bioconductor

Test coverage

Line coverage

–

Expression

–

Tests / Examples

–

Functions

23 18 exported

Complexity

5.3 avg / 17 max

Call network

23 nodes / 5 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

6,213

Files

52

Compiled share

0%

Has compiled src

No

Language breakdown

R 3,376 (54.3%)Tests 179 (2.9%)Docs 2,065 (33.2%)Vignettes 593 (9.5%)

API

Exported functions

19

Internal functions

5

Recent export changes

v3.20+19 SummarizedCounts, calc_gene_gc, calc_region_gc +16 more

Testing

Has tests

Yes

Test-to-code ratio

0.05

testthat edition

3

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

100%

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.4.0

System requirements

–

C++ standard

–

License

GPL-3

License flags

SPDX valid, OSI approved

History

Versions

4

First release

2024-10-29

Latest release

2026-04-28

Avg cadence

181 days

Cold removal rate

–

Dep drift

2

LOC over versions

v3.20: 6,222 LOCv3.21: 6,213 LOCv3.22: 6,213 LOCv3.23: 6,213 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

In the Bioconductor 3.23 release
READMEYes · 47 wordsVignettesYes · 1 · dynamicNEWSYes · 100% structuredCitation fileYes · cites a publicationWebsitenot declared in DESCRIPTION
Help pages
24 (1 internal)includes a package overview page
Examples that run
100%18 run in a plain check (6 of them under a condition)
Exported functions with examples
95%
Documented parameters
94%
Return-value docs
95%
Help pages citing references
0%

Repository practices

Upstream repositoryBeta

Checks run against github.com/haibol2016/cleanuprnaseq on 2026-10-11.

No development-tooling practices detected in the upstream repository.

How this is detected·Detection ruleset v3 (2026-09-26)

Datasets

Bundled datasets · 5
NameClassSizeAlso in
example.colDatadata.frame8 × 6No other package
feature_counts_listlist7 elementsNo other package
gene_GCdata.frame62,754 × 2No other package
intergenic_GCdata.frame2,000 × 2No other package
salmon_quantlist3 elementsNo other package

All of CleanUpRNAseq's data objects

Topics

Maintainer
Haibo Liu

Available on

CRANr2uBioconductorautoCRANCOPR

People

Cite

Cite this package

Run in R for the authors' entry:

citation("CleanUpRNAseq")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.3390/biotech13030030.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for CleanUpRNAseq version 1.6.0 [Data set]. HJJB, LLC. Data release v2026-10-18. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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