R Observatory: Metrics for nlmixr2extra version 5.2.0

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

nlmixr2extra

5.2.0

Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions

4packages depend

21.8Kdownloads / year

0.2%test coverage

13/13checks pass

Overview

About

Maintained by Matthew FidlerFirst published 2022-05-1711 releasesCRAN page ↗GitHub ↗

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 doi:10.1007/s10928-015-9409-1). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 doi:10.1002/psp4.12052). This package is for support functions like preconditioned fits doi:10.1208/s12248-016-9866-5, boostrap and stepwise covariate selection.

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)

install.packages("nlmixr2extra", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("nlmixr2/nlmixr2extra")

Development version from nlmixr2/nlmixr2extra. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-nlmixr2extra

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-nlmixr2extra

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

Health

CRAN checks

13OK

Slowest check: 5.2 min · r-devel-windows-x86_64

Code health

Yes

Tests · ratio 0.50

0.2%

Coverage · measured lines

100%

Documentation · exports

19

Dependencies · direct

Check history

OK2026-08-12
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-08-04
10 OK · 1 NOTE · 0 WARNING · 2 ERROR · 0 FAILURE
NOTE2026-08-01
12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
OK2026-04-22
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-04-18
13 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE

Show 1 earlier snapshots

OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMEYes · 78 wordsVignettesNopkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo

Examples that run: 22%
Documented parameters: 98%
Return-value docs: 87%
References docs: 4%

Downloads

21.8K

CRAN downloads in the past year

Rank #2,865 · ~60/day · ~1.8K/mo

Releases R versions

Daily download trend is not available in this view yet.

1.6K30 days

5K90 days

21.8K1 year

Compare downloads with other packages →

Also on727 r2u18.4K conda_forge18 c2d4u

Repository

GitHub ↗ nlmixr2/nlmixr2extra

7Stars

3Forks

29Open issues

0Open PRs

11Releases

453Commits

5Contributors

License GPL-3.0 · 453 commits · Last activity 2026-08-19

Releases over time

2026-07-14 · 102026-08-05 · 11

Repository practices

Upstream repositoryBeta

5 development-tooling and community-health practices detected across 4 families in the upstream repository

Checks run against github.com/nlmixr2/nlmixr2extra on 2026-08-16.

Continuous integration (1)

GitHub Actions

CRAN release process (2)

cran-comments.mdCRAN-SUBMISSION

Docs source (1)

README.Rmd

Coverage (1)

Codecov

How this is detected·Detection ruleset v1 (2026-07-18)

Development tooling

AI-assisted toolingBeta

Uses AI-assisted development tooling (declared in repo)

Earliest detected marker: claude on 2026-04-03

claude

Most recent: claude on 2026-04-03

Evidence

claude: on 2026-04-03 · evidence B, D

How this is detected·Detection ruleset v2 (updated 2026-07-29)

Dependencies

Declared dependencies

26 external dependencies (excludes base and recommended)

Depends (1)

R >= 4.1

Imports (19)

checkmate cli crayon data.table digest dplyr ggplot2 ggtext knitr lotri magrittrmethodsnlmenlmixr2est Rcpp rxode2statssymengineutils

LinkingTo (2)

Rcpp RcppArmadillo

Suggests (9)

brms nlmixr2data pander rmarkdown tidyr nlmixr2lib testthat tibble withr

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

4direct

2indirect

babelmixr2 nlmixr2 nlmixr2plot nlmixr2rpt

Code & Tests

Datasets

People & History

People (6)

Maintainer (1)

Matthew Fidler

Author, Maintainer

Authors (4)

Matthew Fidler

Author, Maintainer

Bill Denney

Author · added in 2.0.9

Vipul Mann

Author

Vishal Sarsani

Author · added in 2.0.7

Contributors (2)

Christian Bartels

Contributor · added in 2.0.7

Omar Elashkar

Contributor · added in 5.1.0

Package Timeline

11 releases. Pick two to compare their code metrics. R releases are shown for context.

5.2.0Latest
2026-08-05 · current release · diff ↗
5.1.0
2026-06-07 · diff ↗
R
R 4.6.0 released · 2026-04-24
5.0.0
2025-11-29 · diff ↗
R
R 4.5.0 released · 2025-04-11
3.0.2
2025-02-17 · diff ↗
3.0.1
2024-10-29 · diff ↗
3.0.0
2024-09-18 · diff ↗
2.0.10
2024-05-29 · diff ↗
R
R 4.4.0 released · 2024-04-24
2.0.9
2024-01-31 · diff ↗
R
R 4.3.0 released · 2023-04-21
2.0.8
2022-10-23 · diff ↗
2.0.7
2022-10-20 · diff ↗
2.0.6
2022-05-17
R
R 4.2.0 released · 2022-04-22

Package metadata

First published: 2022-05-17
Total releases: 11 / 4 yrs
License: GPL (>= 3) OSI
Minimum R: ≥ 4.1
Bundled data: 54 KB / 1 file
Download size: 172 KB
Installed size: not tracked yet
With dependencies: not tracked yet

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("nlmixr2extra")

Format

Fidler, M., Bartels, C., Denney, B., Elashkar, O., Mann, V., & Sarsani, V. (2026). nlmixr2extra: Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions (Version 5.2.0) [Computer software]. https://doi.org/10.32614/CRAN.package.nlmixr2extra

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for nlmixr2extra version 5.2.0 [Data set]. HJJB, LLC. Data release v2026-08-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

Report a problem with this page →