R Observatory: Metrics for nlmixr2lib version 0.3.2

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

nlmixr2lib

0.3.2Package record

A Model Library for 'nlmixr2'

0packages dependsuggested by 4

4.7Kdownloads / year

97.5%test coverage

13/13flavors OK

Overview

About

Maintained by Bill DenneyCRAN page ↗GitHub ↗Website ↗

A model library for 'nlmixr2'. The models include (and plan to include) pharmacokinetic, pharmacodynamic, and disease models used in pharmacometrics. Where applicable, references for each model are included in the meta-data for each individual model. The package also includes model composition and modification functions to make model updates easier.

Changes in 0.3.2

Add Kim 2006 model for IgG metabolism
Add Xie 2019 agomelatine PK model
Drop qs since it will be archived
Update tumor growth inhibition models
addResErr() now works with multiple-endpoint models
Additional testing

From NEWS.md in the release

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)

install.packages("nlmixr2lib", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("nlmixr2/nlmixr2lib")

Development version from nlmixr2/nlmixr2lib. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-nlmixr2lib

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled. We list this channel from recorded r2u download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-nlmixr2lib

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

Health

CRAN checks

13OK

CRAN check page ↗

Slowest check: 4.6 min · r-oldrel-windows-x86_64

Status changes

OK13 OK2026-10-03
ERROR11 OK, 2 ERROR2026-09-12
OK13 OK2026-08-12
ERROR10 OK, 1 NOTE, 2 ERROR2026-08-04
NOTE12 OK, 1 NOTE2026-08-01

Show 9 earlier changesHide 9 earlier changes

OK13 OK2026-06-17
ERROR12 OK, 1 ERROR2026-06-15
OK13 OK2026-04-30
ERROR12 OK, 1 ERROR2026-04-28
OK14 OK2026-04-22
ERROR13 OK, 1 ERROR2026-04-18
OK14 OK2026-03-29
ERROR13 OK, 1 ERROR2026-03-25
OK14 OK2026-03-10

Advisories

none known

How this is measured·How advisories are found

Documentation

In release 0.3.2

READMEYes · 149 wordsVignettesYes · 5 · dynamicNEWSYes · 100% structured · mentions 0.3.2Citation fileNoWebsiteYes · pkgdown

The repository also keeps web-only articles.

Help pages: 36 (1 internal)
Examples that run: 97%31 run in a plain check · 1 only when donttest examples are enabled (R CMD check --as-cran)
Exported functions with examples: 91%
Documented parameters: 95%
Return-value docs: 94%
Help pages citing references: 0%

Vignettes (5)

Creating a model library HTML
Kyhl_2016_nalmefene HTML
List of models HTML
Trontinemab and gantenerumab PK in plasma and brain (Grimm 2023) HTML
Xie_2019_agomelatine HTML

How these are measured

Downloads

4.7K

CRAN downloads in the past year

Rank #5,590 · ~13/day · ~396/mo

Releases R versions

Daily download trend is not available in this view yet.

62230 days

1.5K90 days

4.7K1 year

Compare downloads with other packages →

Also on110 r2u

How downloads are counted

Repository

nlmixr2/nlmixr2lib ↗Organization: nlmixr2

14Stars

6Forks

7Open issues

4Open PRs

5Releases

6,827Commits

10Commit identities

6,827 commits · Last activity 2026-10-10 · +7.7% stars, 30d · Default branch at 0.3.2.9000, ahead of CRAN 0.3.2 (checked 2026-10-18)

Responsiveness

How these are sampled

PRs merged (all time): 95%
Median days to close, 50 most recently updated closed issues: 17
Median days to close, 50 most recently updated closed PRs: 0

Stars over time

2026-07-14 · 112026-09-23 · 14

How these are measured

PracticesBeta

13 development-tooling and community-health practices detected across 7 families in the upstream repository

Checks run against github.com/nlmixr2/nlmixr2lib on 2026-10-18.

Continuous integration (2)

GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (3)

pkgdown

GitHub Pages site last deployed 2026-10-10 · The repository has a site deploy workflow

pkgdown site last built 2026-10-10

Coverage (1)

Coverage reporting (Codecov)

Reproducibility and dev environment (1)

data-raw/

Show all practicesHide 3 practices

CRAN release process (1)

cran-comments.md

Lint, format, editor (3)

lintrLint workflowAir

Git structural (2)

.gitattributesblame-ignore revs

How this is detected·Detection ruleset v3 (2026-09-26)

AI coding toolsBeta

This repository shows signs of AI coding tools.

GitHub Copilotfirst seen 2026-01-22
Pull request: opened by its own account
Commits: 2 by its own account
Claude Codefirst seen 2026-04-08
Seen in the repository: .claude, .claude/skills, CLAUDE.md
Named in .Rbuildignore: .claude, CLAUDE.md
Named in .gitignore: .claude
Pull request it wrote: opened by a project member
Commits: at least 3,588 crediting it in the message

From outside contributors

Claude Code
Pull requests: 178 from outside contributors, first on 2026-04-18, 1 from forks

Models named in its commits

Claude Opus 4.773 commits · Apr to Jun 2026
Claude Sonnet 4.623 commits · Apr 2026
Claude Opus 4.64 commits · Apr 2026
Claude Opus 51 commit · Jul 2026

Some of these counts are a minimum, because the search stopped before the oldest commits.

Counts are commits, not lines of code. Commits by a tool's accounts count once across all of its accounts. Commits crediting it are the largest count among its credit lines, a minimum.How this is detected·Detection ruleset v4 (updated 2026-09-27)

Dependencies

Declared dependencies

13 external dependencies (excludes base and recommended)

Installing nlmixr2lib adds 66 packages (42 with compiled code, 71 MB of source tarballs). Heaviest: BH 14 MB, stringi 11 MB, ggplot2 6.0 MB.

Depends (1)

R >= 4.1

Imports (5)

checkmate climethodsnlmixr2est rxode2

LinkingTo (0)

none

Suggests (9)

covr dplyr knitr rmarkdown testthat qs2 tidyr ggplot2 withr

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Suggested by 4

Suggests, most downloaded first

nlmixr2extra nlmixr2 babelmixr2 ruminate

How these are counted

Code & Tests

Datasets

People & History

People (4)

Bill Denney

Author, Maintainer since 0.1.0 (2022)

Matthew Fidler

Author

Richard Hooijmaijers

Author

Kiranmayi Vedantham

Author · added in 0.3.2

Releases (5)

Pick two releases to compare their code metrics.

R
R 4.6.0 released · 2026-04-24
0.3.2Latest
record
2026-01-18 · current release · diff ↗
0.3.1
record
2025-10-22 · diff ↗
R
R 4.5.0 released · 2025-04-11
0.3.0
record
2024-10-07 · diff ↗ ·
added 52 exports
addBaseline1exp, addBaselineConst, addBaselineExp, addBaselineLin, addBioavailability, addCmtProp, addDepot, addDirectLin, addDur, addEffectCmtLin, addIndirect, addIndirectLin, addIni, addLag, addLogEstimates, addRate, addTransit, addWeibullAbs, assertCompartmentExists, assertCompartmentName, assertParameterValue, assertRxUi, assertRxUiEstimatedResiduals, assertRxUiMixedOnly, assertRxUiMuRefOnly, assertRxUiNormal, assertRxUiPopulationOnly, assertRxUiPrediction, assertRxUiRandomOnIdOnly, assertRxUiSingleEndpoint and 22 more
R
R 4.4.0 released · 2024-04-24
R
R 4.3.0 released · 2023-04-21
0.2.0
record
2023-03-29 · diff ↗ ·
removed 1 export
%>%

added 1 export
updateOncologyXenograftSimeoni2004
0.1.0
record
2022-10-31
R
R 4.2.0 released · 2022-04-22

Package metadata

First published: 2022-10-31
Total releases: 5 / 4 yrs
License: GPL (>= 2) OSI
Minimum R: ≥ 4.1
Bundled data: 3.2 KB / 1 file
Download size: 156 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("nlmixr2lib")

Format

Denney, B., Fidler, M., Hooijmaijers, R., & Vedantham, K. (2026). nlmixr2lib: A Model Library for 'nlmixr2' (Version 0.3.2) [Computer software]. https://doi.org/10.32614/CRAN.package.nlmixr2lib

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for nlmixr2lib version 0.3.2 [Data set]. HJJB, LLC. Data release v2026-10-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

Report a problem with this page →