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treekoR

Bioc current

Cytometry Cluster Hierarchy and Cellular-to-phenotype Associations

v1.20.0 · Package record · software · GPL-3

Release Lineage

Entered 3.13 · May 20, 2021

Current · Requires R 4.6

1.0 In 11 of 49 releases 3.23

Description

treekoR is a novel framework that aims to utilise the hierarchical nature of single cell cytometry data to find robust and interpretable associations between cell subsets and patient clinical end points. These associations are aimed to recapitulate the nested proportions prevalent in workflows inovlving manual gating, which are often overlooked in workflows using automatic clustering to identify cell populations. We developed treekoR to: Derive a hierarchical tree structure of cell clusters; quantify a cell types as a proportion relative to all cells in a sample (%total), and, as the proportion relative to a parent population (%parent); perform significance testing using the calculated proportions; and provide an interactive html visualisation to help highlight key results.

Advisories

None published for Bioconductor

Test coverage

Line coverage

–

Expression

–

Tests / Examples

–

Functions

19 9 exported

Complexity

2.7 avg / 11 max

Call network

19 nodes / 13 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

2,644

Files

32

Compiled share

0%

Has compiled src

No

Language breakdown

R 1,301 (49.2%)Tests 309 (11.7%)Docs 821 (31.1%)Vignettes 213 (8.1%)

API

Exported functions

9

Internal functions

10

Testing

Has tests

Yes

Test-to-code ratio

0.24

testthat edition

3

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

–

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.1

System requirements

–

C++ standard

–

License

GPL-3

License flags

SPDX valid, OSI approved

History

Versions

11

First release

2021-05-19

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

–

Dep drift

5

LOC over versions

v3.13: 2,012 LOCv3.14: 2,628 LOCv3.15: 2,628 LOCv3.16: 2,644 LOCv3.17: 2,644 LOCv3.18: 2,644 LOCv3.19: 2,644 LOCv3.20: 2,644 LOCv3.21: 2,644 LOCv3.22: 2,644 LOCv3.23: 2,644 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

In the Bioconductor 3.23 release
READMEYes · 189 wordsVignettesYes · 1 · dynamicNEWSYesCitation fileNoWebsitenot declared in DESCRIPTION
Help pages
20
Examples that run
100%10 run in a plain check
Exported functions with examples
100%
Documented parameters
100%
Return-value docs
100%
Help pages citing references
5%
Vignettes (1)

Repository practices

Bioconductor git repository

Checks read the Bioconductor git repository (git.bioconductor.org), branch RELEASE_3_23.

No development-tooling practices detected in the Bioconductor git repository.

Datasets

Bundled datasets · 1
NameClassSizeAlso in
DeBiasi_COVID_CD8_samp–––

All of treekoR's data objects

Topics

Maintainer
Adam Chan

Available on

CRANr2uBioconductorautoCRANCOPR

Depended on by (2)

Bioconductor (2)

Suggested by (1)

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("treekoR")
Chan, A., & Patrick, E. (2026). treekoR: Cytometry Cluster Hierarchy and Cellular-to-phenotype Associations (Version 1.20.0) [Computer software]. https://bioconductor.org/packages/treekoR

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for treekoR version 1.20.0 [Data set]. HJJB, LLC. Data release v2026-10-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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