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monocle

Bioc current

Clustering, differential expression, and trajectory analysis for single- cell RNA-Seq

v2.40.0 · software · Artistic-2.0

Release Lineage

Entered 3.0 · Oct 14, 2014

Current · Requires R 4.6

1.0 In 24 of 49 releases 3.23

Description

Monocle performs differential expression and time-series analysis for single-cell expression experiments. It orders individual cells according to progress through a biological process, without knowing ahead of time which genes define progress through that process. Monocle also performs differential expression analysis, clustering, visualization, and other useful tasks on single cell expression data. It is designed to work with RNA-Seq and qPCR data, but could be used with other types as well.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

139 61 exported

Complexity

5.5 avg / 34 max

Call network

139 nodes / 165 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

17,342

Files

166

Compiled share

0.6%

Has compiled src

Yes

Language breakdown

R 8,660 (49.9%)C/C++/src 98 (0.6%)Tests 1,512 (8.7%)Docs 3,234 (18.6%)Vignettes 3,838 (22.1%)

API

Exported functions

61

Internal functions

70

Recent export changes

v3.8−1 selectNegentropyGenes
v3.6+6 exportCDS, importCDS, plot_complex_cell_trajectory +3 more

Testing & CI

Has tests

Yes

Test-to-code ratio

0.17

testthat edition

CI present

Yes

CI type

["travis"]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

0

Dep constraint coverage

30.3%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

2.10.0

System requirements

C++ standard

License

Artistic-2.0

License flags

SPDX valid, OSI approved

History

Versions

24

First release

2014-10-13

Latest release

2026-04-28

Avg cadence

181 days

Cold removal rate

100%

Dep drift

21

LOC over versions

v3.0: 4,112 LOCv3.1: 4,211 LOCv3.2: 4,211 LOCv3.3: 4,211 LOCv3.4: 12,093 LOCv3.5: 13,491 LOCv3.6: 17,235 LOCv3.7: 17,229 LOCv3.8: 17,082 LOCv3.9: 17,082 LOCv3.10: 17,082 LOCv3.11: 17,082 LOCv3.12: 17,082 LOCv3.13: 17,082 LOCv3.14: 17,419 LOCv3.15: 17,337 LOCv3.16: 17,337 LOCv3.17: 17,341 LOCv3.18: 17,342 LOCv3.19: 17,342 LOCv3.20: 17,342 LOCv3.21: 17,342 LOCv3.22: 17,342 LOCv3.23: 17,342 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 83 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo
Examples that run
0%
Documented parameters
95%
Return-value docs
86%
References docs
1%

Topics

Depended on by (8)

CRAN (1)

People

Cole Trapnell

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("monocle")

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for monocle version 2.40.0 [Data set]. HJJB, LLC. Data release v2026-08-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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