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missMethyl

Bioc current

Analysing Illumina HumanMethylation BeadChip Data

v1.46.0 · Package record · software · GPL-2

Release Lineage

Entered 3.0 · Oct 14, 2014

Current · Requires R 4.6

1.0 In 24 of 49 releases 3.23

Description

Normalisation, testing for differential variability and differential methylation and gene set testing for data from Illumina's Infinium HumanMethylation arrays. The normalisation procedure is subset-quantile within-array normalisation (SWAN), which allows Infinium I and II type probes on a single array to be normalised together. The test for differential variability is based on an empirical Bayes version of Levene's test. Differential methylation testing is performed using RUV, which can adjust for systematic errors of unknown origin in high-dimensional data by using negative control probes. Gene ontology analysis is performed by taking into account the number of probes per gene on the array, as well as taking into account multi-gene associated probes.

Advisories

None published for Bioconductor

Test coverage

Line coverage

–

Expression

–

Tests / Examples

–

Functions

34 18 exported

Complexity

4.6 avg / 20 max

Call network

34 nodes / 20 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

6,791

Files

36

Compiled share

0%

Has compiled src

No

Language breakdown

R 3,349 (49.3%)Docs 2,197 (32.4%)Vignettes 1,245 (18.3%)

API

Exported functions

18

Internal functions

16

Recent export changes

v3.9+1 getAdj  −1 getAdjusted
v3.8+1 getAdjusted

Testing

Has tests

No

Test-to-code ratio

0.00

testthat edition

–

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

3.6.0

System requirements

–

C++ standard

–

License

GPL-2

License flags

SPDX valid, OSI approved

History

Versions

24

First release

2014-10-13

Latest release

2026-04-28

Avg cadence

183 days

Cold removal rate

100%

Dep drift

21

LOC over versions

v3.0: 1,092 LOCv3.1: 2,188 LOCv3.2: 2,187 LOCv3.3: 2,588 LOCv3.4: 3,023 LOCv3.5: 3,041 LOCv3.6: 3,041 LOCv3.7: 3,047 LOCv3.8: 3,366 LOCv3.9: 3,447 LOCv3.10: 3,966 LOCv3.11: 5,591 LOCv3.12: 6,631 LOCv3.13: 6,633 LOCv3.14: 6,633 LOCv3.15: 6,633 LOCv3.16: 6,634 LOCv3.17: 6,635 LOCv3.18: 6,635 LOCv3.19: 6,635 LOCv3.20: 6,790 LOCv3.21: 6,790 LOCv3.22: 6,791 LOCv3.23: 6,791 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

In the Bioconductor 3.23 release
READMENoVignettesYes · 1 · dynamicNEWSYesCitation fileYes · cites a publicationWebsitenot declared in DESCRIPTION
Help pages
19includes a package overview page
Examples that run
67%12 run in a plain check · 6 never run
Exported functions with examples
100%
Documented parameters
97%
Return-value docs
100%
Help pages citing references
63%

Repository practices

Bioconductor git repository

Checks read the Bioconductor git repository (git.bioconductor.org), branch RELEASE_3_23.

No development-tooling practices detected in the Bioconductor git repository.

Topics

Maintainer
Belinda Phipson

Available on

CRANr2uBioconductorautoCRANCOPR

Depended on by (5)

Suggested by (1)

People (from the free-text Author field)

Cite

Cite this package

Run in R for the authors' entry:

citation("missMethyl")

The package provides a citation file, so citation() returns the authors' own entry.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for missMethyl version 1.46.0 [Data set]. HJJB, LLC. Data release v2026-10-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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