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decompTumor2Sig

Bioc current

Decomposition of individual tumors into mutational signatures by signature refitting

v2.28.1 · Package record · software · GPL-2

Release Lineage

Entered 3.9 · May 3, 2019

Current · Requires R 4.6

1.0 In 15 of 49 releases 3.23

Description

Uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.

Advisories

None published for Bioconductor

Test coverage

Line coverage

–

Expression

–

Tests / Examples

–

Functions

66 24 exported

Complexity

6.5 avg / 51 max

Call network

66 nodes / 121 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

10,536

Files

132

Compiled share

0%

Has compiled src

No

Language breakdown

R 5,798 (55%)Docs 3,381 (32.1%)Vignettes 1,357 (12.9%)

API

Exported functions

24

Internal functions

42

Recent export changes

v3.9+23 composeGenomesFromExposures, computeExplainedVariance, convertAlexandrov2Shiraishi +20 more

Testing

Has tests

No

Test-to-code ratio

0.00

testthat edition

–

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

–

Unsafe pattern score

0

Dep constraint coverage

4.5%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.0

System requirements

–

C++ standard

–

License

GPL-2

License flags

SPDX valid, OSI approved

History

Versions

15

First release

2019-05-02

Latest release

2026-07-21

Avg cadence

182 days

Cold removal rate

–

Dep drift

5

LOC over versions

v3.9: 9,941 LOCv3.10: 10,056 LOCv3.11: 9,662 LOCv3.12: 9,662 LOCv3.13: 10,531 LOCv3.14: 10,531 LOCv3.15: 10,531 LOCv3.16: 10,535 LOCv3.17: 10,535 LOCv3.18: 10,535 LOCv3.19: 10,535 LOCv3.20: 10,535 LOCv3.21: 10,535 LOCv3.22: 10,535 LOCv3.23: 10,536 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

In the Bioconductor 3.23 release
READMEYes · 24 wordsVignettesYes · 1 · dynamicNEWSYes · 67% structured · mentions 2.28.1Citation fileYes · cites a publicationWebsiteYes
Help pages
66 (41 internal)includes a package overview page
Examples that run
100%24 run in a plain check
Exported functions with examples
100%
Documented parameters
98%
Return-value docs
100%
Help pages citing references
100%
Changes in 2.28.1 (Bioconductor 3.23)
  • Fix: relpaced non existent default URL for readAlexandrovSignatures(); NOTE: in future versions, no default will be specified anymore!

From inst/NEWS in the release

Repository practices

Upstream repositoryBeta

Checks run against github.com/rmpiro/decomptumor2sig on 2026-10-22.

No development-tooling practices detected in the upstream repository.

How this is detected·Detection ruleset v4 (2026-10-20)

Datasets

Bundled datasets · 9
NameClassSizeAlso in
G–––
Nik-Zainal_PMID_22608084-MPF–––
Nik-Zainal_PMID_22608084-pmsignature-sig1data.frame5 × 6No other package
Nik-Zainal_PMID_22608084-pmsignature-sig2data.frame5 × 6No other package
Nik-Zainal_PMID_22608084-pmsignature-sig3data.frame5 × 6No other package
Nik-Zainal_PMID_22608084-pmsignature-sig4data.frame5 × 6No other package
Param–––
genomeslist21 elementsNo other package
signatureslist15 elementsNo other package

All of decompTumor2Sig's data objects

Topics

Maintainer
Rosario M. Piro

Available on

CRANr2uBioconductorautoCRANCOPR

Depended on by (1)

Bioconductor (1)

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("decompTumor2Sig")

The package provides a citation file that builds its entry when R runs it. Run citation() to see it.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for decompTumor2Sig version 2.28.1 [Data set]. HJJB, LLC. Data release v2026-10-25. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-25, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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