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compartmap

Bioc removed

Higher-order chromatin domain inference in single cells from scRNA-seq and scATAC-seq

v1.22.0 · GPL-3 + file LICENSE

Release Lineage

Entered 3.8 · Oct 31, 2018

Removed after 3.19 · May 1, 2024

1.0 In 12 of 49 releases 3.23

Description

Compartmap performs direct inference of higher-order chromatin from scRNA-seq and scATAC-seq. This package implements a James-Stein estimator for computing single-cell level higher-order chromatin domains. Further, we utilize random matrix theory as a method to de-noise correlation matrices to achieve a similar "plaid-like" patterning as observed in Hi-C and scHi-C data.

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