TBSignatureProfiler

Description

Gene signatures of TB progression, TB disease, and other TB disease states have been validated and published previously. This package aggregates known signatures and provides computational tools to enlist their usage on other datasets. The TBSignatureProfiler makes it easy to profile RNA-Seq data using these signatures and includes common signature profiling tools including ASSIGN, GSVA, and ssGSEA. Original models for some gene signatures are also available. A shiny app provides some functionality alongside for detailed command line accessibility.

Code

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Topics

Depended on by (1)

People

• Kiloni Quiles maintainer
• David Jenkins author org
• W. Evan Johnson author
• Christian Love contributor
• Aubrey R. Odom author dtm
• Xutao Wang author
• Yue Zhao contributor