MethReg
Bioc currentAssessing the regulatory potential of DNA methylation regions or sites on gene transcription
Release Lineage
Entered 3.12 · Oct 28, 2020
Current · Requires R 4.6
Description
Epigenome-wide association studies (EWAS) detects a large number of DNA methylation differences, often hundreds of differentially methylated regions and thousands of CpGs, that are significantly associated with a disease, many are located in non-coding regions. Therefore, there is a critical need to better understand the functional impact of these CpG methylations and to further prioritize the significant changes. MethReg is an R package for integrative modeling of DNA methylation, target gene expression and transcription factor binding sites data, to systematically identify and rank functional CpG methylations. MethReg evaluates, prioritizes and annotates CpG sites with high regulatory potential using matched methylation and gene expression data, along with external TF-target interaction databases based on manually curation, ChIP-seq experiments or gene regulatory network analysis.
Test coverage
Line coverage
–
Expression
–
Tests / Examples
–
Functions
80 24 exported
Complexity
4.1 avg / 36 max
Call network
80 nodes / 128 edges
Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.
Call graph
Open call graph →Lowest coverage
Per-function coverage is not measured for this package yet.
Code
Structure
Lines of code
9,678
Files
90
Compiled share
0%
Has compiled src
No
Language breakdown
API
Exported functions
24
Internal functions
56
Recent export changes
Testing & CI
Has tests
Yes
Test-to-code ratio
0.19
testthat edition
–
CI present
No
CI type
[]
PR gated
No
Docs
Roxygen coverage
100%
Health & Security signals
Informational signals; not verdicts.
on.exit coverage
0%
Unsafe pattern score
0
Dep constraint coverage
0%
Secret pattern count
0
Bundled 3rd-party code
2 items
Portability & License
Min R version
4.0
System requirements
–
C++ standard
–
License
GPL-3
License flags
SPDX valid, OSI approved
History
Versions
12
First release
2020-10-27
Latest release
2026-04-28
Avg cadence
182 days
Cold removal rate
100%
Dep drift
8
LOC over versions
Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.
Documentation
- Examples that run
- 95%
- Documented parameters
- 100%
- Return-value docs
- 96%
- References docs
- 0%
Topics
People
- Tiago Silva author maintainer
- Lily Wang author
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("MethReg")This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.