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DOSE

Bioc current

Disease Ontology Semantic and Enrichment analysis

v4.6.0 · software · Artistic-2.0

Release Lineage

Entered 2.9 · Nov 1, 2011

Current · Requires R 4.6

1.0 In 30 of 49 releases 3.23

Description

This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enrichment analysis are also implemented for discovering disease associations of high-throughput biological data.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

33 14 exported

Complexity

2.8 avg / 12 max

Call network

33 nodes / 28 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

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Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

1,932

Files

73

Compiled share

0%

Has compiled src

No

Language breakdown

R 1,073 (55.5%)Tests 22 (1.1%)Docs 775 (40.1%)Vignettes 62 (3.2%)

API

Exported functions

17

Internal functions

19

Recent export changes

v3.9+1 parse_ratio
v3.8−1 enrichMap

Testing & CI

Has tests

Yes

Test-to-code ratio

0.02

testthat edition

CI present

Yes

CI type

["github-actions"]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

25%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

3.5.0

System requirements

C++ standard

License

Artistic-2.0

License flags

SPDX valid, OSI approved

History

Versions

30

First release

2011-10-31

Latest release

2026-04-28

Avg cadence

189 days

Cold removal rate

100%

Dep drift

39

LOC over versions

v2.9: 679 LOCv2.10: 1,955 LOCv2.11: 1,697 LOCv2.12: 1,700 LOCv2.13: 2,622 LOCv2.14: 3,224 LOCv3.0: 3,685 LOCv3.1: 4,173 LOCv3.2: 4,265 LOCv3.3: 4,445 LOCv3.4: 5,595 LOCv3.5: 5,667 LOCv3.6: 5,790 LOCv3.7: 5,295 LOCv3.8: 4,592 LOCv3.9: 4,257 LOCv3.10: 4,261 LOCv3.11: 4,411 LOCv3.12: 4,068 LOCv3.13: 4,069 LOCv3.14: 4,081 LOCv3.15: 4,095 LOCv3.16: 4,176 LOCv3.17: 4,186 LOCv3.18: 4,941 LOCv3.19: 4,126 LOCv3.20: 3,930 LOCv3.21: 3,930 LOCv3.22: 3,930 LOCv3.23: 1,932 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 108 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo
Examples that run
60%
Documented parameters
100%
Return-value docs
93%
References docs
11%

Topics

Depended on by (40)

CRAN (3)

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("DOSE")
Yu, G., Dall'Olio, G., Petyuk, V., & Wang, L. (2026). DOSE: Disease Ontology Semantic and Enrichment analysis (Version 4.6.0) [Computer software]. https://bioconductor.org/packages/DOSE

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for DOSE version 4.6.0 [Data set]. HJJB, LLC. Data release v2026-08-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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