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derfinder

1.46.0Bioconductor

Annotation-agnostic differential expression analysis of RNA-seq data at base-pair resolution via the DER Finder approach

BiocManager::install("derfinder")
Distinct IPs a month, method
1,352Rank 299 in its category
Bioconductor releases
24since 2014
Advisories, method
None publishedfor Bioconductor

This package provides functions for annotation-agnostic differential expression analysis of RNA-seq data. Two implementations of the DER Finder approach are included in this package: (1) single base-level F-statistics and (2) DER identification at the expressed regions-level. The DER Finder approach can also be used to identify differentially bounded ChIP-seq peaks.

Maintainer
Leonardo Collado-Torres
Last updated
28 Apr 2026
First release
Bioconductor 3.0, 14 Oct 2014

Compare with another package

More details
Releases
24 of 49 Bioconductor releases
Category
software
Needs R
>= 3.5.0
Date
2025-07-21
LazyData
true
RoxygenNote
7.3.2
biocViews (8)
Cite

Package

Run in R for the authors' preferred citation:

citation("derfinder")

The package provides a citation file that builds its entry when R runs it. Run citation() to see it.

R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA
Balamuta, J. J. (2026). R Observatory: Metrics for derfinder version 1.46.0 [Data set]. HJJB, LLC. Data release v2026-10-28. https://doi.org/10.5281/zenodo.21843040
About

From data release v2026-10-28, which the citation names so these numbers can be found later.

Release 3.23: OK 26 Oct 2026

  • kunpeng2, Install

    Install on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.46.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • kunpeng2, Build

    Build on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.46.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • kunpeng2, Check

    Check on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.46.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • nebbiolo1, Install

    Install on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.46.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • nebbiolo1, Build

    Build on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.46.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • nebbiolo1, Check

    Check on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.46.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • 6 OK
Machines (2)
MachineInstallBuildCheck
kunpeng2OKOKOK
nebbiolo1OKOKOK
Devel 3.24: OK
  • lconway, Install

    Install on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • lconway, Build

    Build on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • lconway, Check

    Check on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • lconway, Build binary

    Build binary on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • nebbiolo2, Install

    Install on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • nebbiolo2, Build

    Build on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • nebbiolo2, Check

    Check on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • taishan, Install

    Install on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • taishan, Build

    Build on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • taishan, Check

    Check on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.47.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    26 Oct 2026
  • 10 OK
MachineInstallBuildCheckBuild binary
lconwayOKOKOKOK
nebbiolo2OKOKOK
taishanOKOKOK
Built files (4)
PlatformKindFile
macOS (Intel)binaryderfinder_1.46.0.tgz
macOS (Apple Silicon)binaryderfinder_1.46.0.tgz
sourcesourcederfinder_1.46.0.tar.gz
Windowsbinaryderfinder_1.46.0.zip
Total downloads in the latest complete month
7,495It comes from Bioconductor alone. r2u and Bioconda were counted over another window, so they are not added.

Rank in category, by distinct IPs

299 of 3,170

Bioconductor

7,495 downloads in the latest complete month

Distinct IP addresses average 1,352 a month over 12 months, which is a different measure and is never added.

It is in the total. Take it out

r2u

119 downloads in the last 30 days

It is not added because it has no figure for the latest complete month. Show the last 30 days

Bioconda

441 downloads in the last 30 days

It is not added because it has no figure for the latest complete month. Show the last 30 days

This local copy has no series over time.

Compare downloads

Functions
49
Public exports
26
Lines of R code
5,970
Median complexity
5
Functions (49)
Size and composition

Lines by kind (11,583)

KindLinesShare
R code5,97052%
Tests9058%
Documentation2,77024%
Guides1,93817%

Lines by language

LanguageLinesShare
R6,87559%
Rd2,77024%
Vignettes1,93817%

Languages are counted from file extensions.

Files
156
R functions
49
Deprecated functions
1
Complexity
Median
5
Mean
7.41
Highest
31
Median lines per function
42
About complexity

Cyclomatic complexity counts the independent paths through a function: 1 is a straight line, higher is harder to test. R functions only.

Call graph figures
R functions
49
Calls
83
Unconnected
11
Groups
1
Growth (24 releases)
Total lines by release
9,028 on 24 Nov 201411,583 on 28 Apr 2026
Release changes

Test coverage is measured for CRAN packages only. Nothing is known for Bioconductor packages, which is not the same as no coverage.

Test cases
41
Lines of tests
905
Exports named in tests
88.5%
Has tests
Yes
Test frameworks
testthat
Test lines per line of code
0.15
Exports documented
100%
Arguments documented
96.6%
Return value documented
100%
Help pages with examples
78.8%
Examples run in checks
100%
Guides (2)
Other documentation
README
Yes, 371 words
Release notes file
Yes
Help pages
33
Lines of documentation
2,770

12 datasets, 6 can be loaded by name

DatasetSizeColumns
annotation33 × 15name, annotation, description, region, distance, subregion and 9 more
fstats
genomeDataGenome samples processed datalength 2
genomeDataRawGenome samples processed datalength 2
genomeFstatsF-statistics for the example data
genomeInfoGenome samples information31 × 5run, library.layout, hapmap.id, gender, pop
genomeRegionsCandidate DERs for example datalength 4
genomicStateGenomic State for Hsapiens.UCSC.hg19.knownGene
optionsStatslength 14
preplength 5
regionslength 4
timeinfolength 11

lcolladotor / derfinder on github.com

Stars
45no change on 30 days ago
Forks
15
Open issues
3
Last commit
31 Mar 2026
Activity
Commits
919
Open pull requests
0
Tagged releases
0
Latest tagged release
–
Issues closed in
9 days (median)
Pull requests closed in
0 days (median)
Pull requests merged
93%
Created
18 Jul 2013
Licence file reads as
–
Development practices (13)
KindFound
Continuous integrationGitHub Actions, R CMD check workflow
The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel
Governance and communityCode of conduct, Contributing guide, Issue templates, Support guide
The repository owner accepts GitHub Sponsors
Docs sourceREADME.Rmd, pkgdown
GitHub Pages site last deployed 2026-03-31
The repository has a site deploy workflow
CoverageCoverage reporting (Codecov)
Lint, format, editorRStudio project

Method, repository practices

Across lcolladotor

Bioconductor git

R releases
  • In Bioconductor
  • Bioconductor release
ReleaseReleasedR
3.23 current29 Apr 20264.6
3.2230 Oct 20254.5
3.2116 Apr 20254.5
3.2030 Oct 20244.4
3.191 May 20244.4
3.1825 Oct 20234.3
3.1726 Apr 20234.3
3.162 Nov 20224.2
Earlier releases (16)
ReleaseReleasedR
3.1527 Apr 20224.2
3.1427 Oct 20214.1
3.1320 May 20214.1
3.1228 Oct 20204.0
3.1128 Apr 20204.0
3.1030 Oct 20193.6
3.93 May 20193.6
3.831 Oct 20183.5
3.71 May 20183.5
3.631 Oct 20173.4
3.525 Apr 20173.4
3.418 Oct 20163.3
3.34 May 20163.3
3.214 Oct 20153.2
3.117 Apr 20153.2
3.014 Oct 20143.1
Entered Bioconductor
Release 3.0, 14 Oct 2014