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mitoClone2

Bioc current

Clonal Population Identification in Single-Cell RNA-Seq Data using Mitochondrial and Somatic Mutations

v1.18.0 · software · GPL-3

Release Lineage

Entered 3.14 · Oct 27, 2021

Current · Requires R 4.6

1.0 In 10 of 49 releases 3.23

Description

This package primarily identifies variants in mitochondrial genomes from BAM alignment files. It filters these variants to remove RNA editing events then estimates their evolutionary relationship (i.e. their phylogenetic tree) and groups single cells into clones. It also visualizes the mutations and providing additional genomic context.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

49 21 exported

Complexity

3.9 avg / 12 max

Call network

49 nodes / 35 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

4,336

Files

75

Compiled share

9.4%

Has compiled src

Yes

Language breakdown

R 2,323 (53.6%)C/C++/src 406 (9.4%)Tests 22 (0.5%)Docs 1,080 (24.9%)Vignettes 505 (11.6%)

API

Exported functions

22

Internal functions

21

Recent export changes

v3.22+2 vireoFit, predictCellAssignment
v3.21+1 exclusionlists

Testing & CI

Has tests

Yes

Test-to-code ratio

0.01

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.4.0

System requirements

2

C++ standard

License

GPL-3

License flags

SPDX valid, OSI approved

History

Versions

10

First release

2021-10-26

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

Dep drift

1

LOC over versions

v3.14: 3,640 LOCv3.15: 3,640 LOCv3.16: 3,640 LOCv3.17: 3,640 LOCv3.18: 3,640 LOCv3.19: 3,640 LOCv3.20: 3,670 LOCv3.21: 3,798 LOCv3.22: 4,336 LOCv3.23: 4,336 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 339 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 0% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
98%
Return-value docs
95%
References docs
0%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("mitoClone2")
Story, B., Mönke, G., & Velten, L. (2026). mitoClone2: Clonal Population Identification in Single-Cell RNA-Seq Data using Mitochondrial and Somatic Mutations (Version 1.18.0) [Computer software]. https://bioconductor.org/packages/mitoClone2

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for mitoClone2 version 1.18.0 [Data set]. HJJB, LLC. Data release v2026-08-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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