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methylSig

Bioc current

MethylSig: Differential Methylation Testing for WGBS and RRBS Data

v1.24.0 · software · GPL-3

Release Lineage

Entered 3.11 · Apr 28, 2020

Current · Requires R 4.6

1.0 In 13 of 49 releases 3.23

Description

MethylSig is a package for testing for differentially methylated cytosines (DMCs) or regions (DMRs) in whole-genome bisulfite sequencing (WGBS) or reduced representation bisulfite sequencing (RRBS) experiments. MethylSig uses a beta binomial model to test for significant differences between groups of samples. Several options exist for either site-specific or sliding window tests, and variance estimation.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

13 9 exported

Complexity

9.4 avg / 38 max

Call network

13 nodes / 3 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

3,828

Files

59

Compiled share

0%

Has compiled src

No

Language breakdown

R 1,352 (35.3%)Tests 1,380 (36.1%)Docs 530 (13.8%)Vignettes 566 (14.8%)

API

Exported functions

9

Internal functions

4

Testing & CI

Has tests

Yes

Test-to-code ratio

1.02

testthat edition

CI present

Yes

CI type

["travis"]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

3.6

System requirements

C++ standard

License

GPL-3

License flags

SPDX valid, OSI approved

History

Versions

13

First release

2020-04-27

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

Dep drift

2

LOC over versions

v3.11: 3,828 LOCv3.12: 3,828 LOCv3.13: 3,828 LOCv3.14: 3,828 LOCv3.15: 3,828 LOCv3.16: 3,828 LOCv3.17: 3,828 LOCv3.18: 3,828 LOCv3.19: 3,828 LOCv3.20: 3,828 LOCv3.21: 3,828 LOCv3.22: 3,828 LOCv3.23: 3,828 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 1,168 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 67% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
100%
Return-value docs
100%
References docs
0%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("methylSig")
Cavalcante, R. G., & Park, Y. (2026). methylSig: MethylSig: Differential Methylation Testing for WGBS and RRBS Data (Version 1.24.0) [Computer software]. https://bioconductor.org/packages/methylSig

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for methylSig version 1.24.0 [Data set]. HJJB, LLC. Data release v2026-08-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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