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crisprBase

Bioc current

Base functions and classes for CRISPR gRNA design

v1.16.0 · Package record · software · MIT + file LICENSE

Release Lineage

Entered 3.15 · Apr 27, 2022

Current · Requires R 4.6

1.0 In 9 of 49 releases 3.23

Description

Provides S4 classes for general nucleases, CRISPR nucleases, CRISPR nickases, and base editors.Several CRISPR-specific genome arithmetic functions are implemented to help extract genomic coordinates of spacer and protospacer sequences. Commonly-used CRISPR nuclease objects are provided that can be readily used in other packages. Both DNA- and RNA-targeting nucleases are supported.

Advisories

None published for Bioconductor

Test coverage

Line coverage

–

Expression

–

Tests / Examples

–

Functions

58 17 exported

Complexity

2.4 avg / 7 max

Call network

58 nodes / 67 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

6,042

Files

114

Compiled share

0%

Has compiled src

No

Language breakdown

R 3,293 (54.5%)Tests 298 (4.9%)Docs 1,658 (27.4%)Vignettes 793 (13.1%)

API

Exported functions

53

Internal functions

41

Recent export changes

v3.22+1 setEditingWeights  −1 editingWeights<-

Testing

Has tests

Yes

Test-to-code ratio

0.09

testthat edition

–

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

–

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.1

System requirements

–

C++ standard

–

License

MIT + file LICENSE

License flags

SPDX valid, OSI approved

History

Versions

9

First release

2022-04-26

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

100%

Dep drift

1

LOC over versions

v3.15: 4,384 LOCv3.16: 5,935 LOCv3.17: 5,971 LOCv3.18: 5,971 LOCv3.19: 5,974 LOCv3.20: 6,015 LOCv3.21: 6,015 LOCv3.22: 6,042 LOCv3.23: 6,042 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

In the Bioconductor 3.23 release
READMEYes · 3,030 wordsVignettesYes · 1 · dynamicNEWSYesCitation fileYes · cites a publicationWebsitenot declared in DESCRIPTION
Help pages
27 (1 internal)
Examples that run
100%16 run in a plain check (1 of them under a condition)
Exported functions with examples
94%
Documented parameters
97%
Return-value docs
94%
Help pages citing references
0%

Repository practices

Upstream repositoryBeta

2 development-tooling and community-health practices detected across 2 families in the upstream repository

Checks run against github.com/crisprverse/crisprbase on 2026-10-21.

Governance and community (1)

The repository owner accepts GitHub Sponsors

Docs source (1)
README.Rmd
How this is detected·Detection ruleset v4 (2026-10-20)

Datasets

Bundled datasets · 10
NameClassSizeAlso in
AsCas12a–––
BE4max–––
CasRx–––
Csm–––
MAD7–––
SaCas9–––
SpCas9–––
SpG–––
enAsCas12a–––
restrictionEnzymeslist4,916 elementsNo other package

3 internal objects are bundled for the package's own use and not listed here.

All of crisprBase's data objects

Topics

Available on

CRANr2uBioconductorautoCRANCOPR

Depended on by (6)

People

Cite

Cite this package

Run in R for the authors' entry:

citation("crisprBase")

The package provides a citation file, so citation() returns the authors' own entry.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for crisprBase version 1.16.0 [Data set]. HJJB, LLC. Data release v2026-10-25. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-25, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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