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BulkSignalR

Bioc current

Infer Ligand-Receptor Interactions from bulk expression (transcriptomics/proteomics) data, or spatial transcriptomics

v1.4.0 · Package record · software · CeCILL | file LICENSE

Release Lineage

Entered 3.21 · Apr 16, 2025

Current · Requires R 4.6

1.0 In 3 of 49 releases 3.23

Description

Inference of ligand-receptor (LR) interactions from bulk expression (transcriptomics/proteomics) data, or spatial transcriptomics. BulkSignalR bases its inferences on the LRdb database included in our other package, SingleCellSignalR available from Bioconductor. It relies on a statistical model that is specific to bulk data sets. Different visualization and data summary functions are proposed to help navigating prediction results.

Advisories

None published for Bioconductor

Test coverage

Line coverage

–

Expression

–

Tests / Examples

–

Functions

79 41 exported

Complexity

6.7 avg / 26 max

Call network

79 nodes / 41 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

18,610

Files

203

Compiled share

0%

Has compiled src

No

Language breakdown

R 11,161 (60%)Tests 11 (0.1%)Docs 6,239 (33.5%)Vignettes 1,199 (6.4%)

API

Exported functions

40

Internal functions

38

Recent export changes

v3.21+40 BSRClusterComp, BSRDataModel, BSRDataModelComp +37 more

Testing

Has tests

Yes

Test-to-code ratio

0.00

testthat edition

3

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

0

Dep constraint coverage

6.7%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.5

System requirements

–

C++ standard

–

License

CeCILL | file LICENSE

License flags

not SPDX, not OSI

History

Versions

3

First release

2025-09-27

Latest release

2026-04-28

Avg cadence

107 days

Cold removal rate

–

Dep drift

2

LOC over versions

v3.21: 18,460 LOCv3.22: 18,611 LOCv3.23: 18,610 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

In the Bioconductor 3.23 release
READMEYes · 239 wordsVignettesYes · 3 · dynamicNEWSYes · 0% structuredCitation fileYes · cites a publicationWebsitenot declared in DESCRIPTION
Help pages
155 (51 internal)includes a package overview page
Examples that run
100%85 run in a plain check
Exported functions with examples
100%
Documented parameters
99%
Return-value docs
100%
Help pages citing references
0%

Repository practices

Upstream repositoryBeta

Checks run against github.com/jcolinge/bulksignalr on 2026-10-22.

No development-tooling practices detected in the upstream repository.

How this is detected·Detection ruleset v4 (2026-10-20)

Datasets

Bundled datasets · 14
NameClassSizeAlso in
annotation.spa–––
bodyMap.mousedata.frame24,543 × 8No other package
bsrdm–––
bsrdm.comp–––
bsrdm.spa–––
bsrinf–––
bsrinf.comp–––
bsrinf.mouse–––
bsrinf.spa–––
immune.signaturesdata.frame1,541 × 2No other package
ortholog.dictdata.frame4,572 × 1No other package
p.EMTdata.frame100 × 1No other package
sdcdata.frame19,764 × 26No other package
tme.signaturesdata.frame213 × 2No other package

All of BulkSignalR's data objects

Topics

Available on

CRANr2uBioconductorautoCRANCOPR

Depended on by (1)

Bioconductor (1)

People

Cite

Cite this package

Run in R for the authors' entry:

citation("BulkSignalR")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.1093/nar/gkad352.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for BulkSignalR version 1.4.0 [Data set]. HJJB, LLC. Data release v2026-10-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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