Resampling-based multiple hypothesis testing
Overview
Non-parametric bootstrap and permutation resampling-based multiple testing procedures (including empirical Bayes methods) for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Several choices of bootstrap-based null distribution are implemented (centered, centered and scaled, quantile-transformed). Single-step and step-wise methods are available. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models as well as those based on correlation parameters) are included. When probing hypotheses with t-statistics, users may also select a potentially faster null distribution which is multivariate normal with mean zero and variance covariance matrix derived from the vector influence function. Results are reported in terms of adjusted p-values, confidence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments.
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Documentation
- Help pages
- 21 (8 internal)
- Examples that run
- 83%15 run in a plain check · 3 hold no code
- Exported functions with examples
- 89%
- Documented parameters
- 87%
- Return-value docs
- 83%
- Help pages citing references
- 62%
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Maintainer since 1.6.0 (2005)
Pick two releases to compare their code metrics.
- RR 2.14.0 released · 2011-10-31
- 2.8.0archived2011-04-26 · diff ↗This package is now available from Bioconductor only, see <https://www.bioconductor.org/packages/release/bioc/html/multtest.html>
- 2.8.02011-04-14 · diff ↗
- RR 2.13.0 released · 2011-04-13
- 2.7.12011-02-01 · diff ↗
- 2.6.02010-10-18 · diff ↗
- RR 2.12.0 released · 2010-10-15
- 2.5.142010-07-29 · diff ↗
- 2.4.02010-04-22 · diff ↗
- RR 2.11.0 released · 2010-04-22
- 2.3.22010-03-10 · diff ↗
- 2.2.02009-11-12 · diff ↗
- RR 2.10.0 released · 2009-10-26
- 2.1.32009-10-13 · diff ↗
- 2.1.12009-06-11 · diff ↗
- 2.0.02009-04-21 · diff ↗ ·
added 18 exports
EBMTP, center.only, quant.trans, corr.Tn, corr.null, IC.Cor.NA, IC.CorXW.NA, insert.NA, diffs.1.N, marg.samp, tQuantTrans, G.VS, ABH.h0, dens.est, Hsets, VScount, mtp2ebmtp, ebmtp2mtp
Show 21 earlier eventsHide 21 earlier events
- RR 2.9.0 released · 2009-04-17
- 1.23.32009-02-13 · diff ↗
- RR 2.8.0 released · 2008-10-20
- 1.21.12008-08-15 · diff ↗
- RR 2.7.0 released · 2008-04-22
- RR 2.6.0 released · 2007-10-03
- 1.16.12007-07-16 · diff ↗
- 1.16.02007-07-02 · diff ↗ ·
added 33 exports
MTP, as.list, mt.maxT, mt.minP, mt.plot, mt.rawp2adjp, mt.reject, mt.sample.label, mt.sample.rawp, mt.sample.teststat, mt.teststat, mt.teststat.num.denum, meanX, diffmeanX, FX, blockFX, twowayFX, lmX, lmY, coxY, get.Tn, boot.null, boot.resample, center.scale, fwer2gfwer, fwer2tppfp, fwer2fdr, get.index, ss.maxT, ss.minP and 3 more - RR 2.5.0 released · 2007-04-24
- 1.8.32007-01-06 · diff ↗
- RR 2.4.0 released · 2006-10-03
- 1.8.22006-09-22 · diff ↗
- RR 2.3.0 released · 2006-04-24
- 1.8.12006-04-04 · diff ↗
- 1.8.02005-11-01 · diff ↗
- RR 2.2.0 released · 2005-10-06
- 1.7.32005-07-06 · diff ↗
- 1.7.22005-07-04 · diff ↗
- 1.7.12005-07-01 · diff ↗
- 1.6.02005-05-30
- RR 2.1.0 released · 2005-04-18
Package metadata
- First published
- 2005-05-30
- Total releases
- 22 / 21 yrs
- License
- LGPL
- Minimum R
- ≥ 2.9.0
- Bundled data
- 441 KB / 1 file
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