R Observatory: Metrics for nlmixr2auto version 1.0.0

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

nlmixr2auto needs 2 packages that CRAN will archive unless their check problems are fixed, the earliest by Oct 22. See which.

nlmixr2auto

1.0.0

Automated Population Pharmacokinetic Modeling

0packages dependsuggested by 1

2.3Kdownloads / year

–test coverage

13/13flavors OK

Overview

About

Maintained by Zhonghui HuangCRAN page ↗GitHub ↗Issues ↗

Automated population pharmacokinetic modeling framework for data-driven initialisation, model evaluation, and metaheuristic optimization. Supports genetic algorithms, ant colony optimization, tabu search, and stepwise procedures for automated model selection and parameter estimation within the nlmixr2 ecosystem.

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)

install.packages("nlmixr2auto", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("ucl-pharmacometrics/nlmixr2auto")

Development version from ucl-pharmacometrics/nlmixr2auto. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-nlmixr2auto

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled. We list this channel from recorded r2u download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-nlmixr2auto

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

Health

CRAN checks

13OK

CRAN check page ↗

Slowest check: 2.9 min · r-oldrel-windows-x86_64

Status changes

OK13 OK2026-10-03
ERROR12 OK, 1 ERROR2026-09-15
OK13 OK2026-08-12
ERROR10 OK, 1 NOTE, 2 ERROR2026-08-04
NOTE12 OK, 1 NOTE2026-08-01

Show 3 earlier changesHide 3 earlier changes

OK13 OK2026-06-09
ERROR12 OK, 1 ERROR2026-06-08
OK14 OK2026-03-10

Advisories

none known

How this is measured·How advisories are found

Documentation

In release 1.0.0

READMENoVignettesNoNEWSNoCitation fileNoWebsitenot declared in DESCRIPTION

Help pages: 56
Examples that run: 67%35 run in a plain check · 17 only when donttest examples are enabled (R CMD check --as-cran)
Exported functions with examples: 100%
Documented parameters: 98%
Return-value docs: 100%
Help pages citing references: 0%

How these are measured

Downloads

2.3K

CRAN downloads in the past year

Rank #7,180 · ~6/day · ~196/mo

Releases R versions

Daily download trend is not available in this view yet.

49930 days

1.2K90 days

2.3K1 year

Compare downloads with other packages →

Also on48 r2u

How downloads are counted

Repository

ucl-pharmacometrics/nlmixr2auto ↗

Responsiveness

not measured

How these are measured

PracticesBeta

Repository github.com/ucl-pharmacometrics/nlmixr2auto is linked, but repository-practices checks have not run for it yet.

How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies

10 external dependencies (excludes base and recommended)

Installing nlmixr2auto adds 147 packages (92 with compiled code, 116 MB of source tarballs). Heaviest: BH 14 MB, stringi 11 MB, ggplot2 6.0 MB.

Depends (2)

R >= 4.1.0nlmixr2data

Imports (9)

nlmixr2 nlmixr2est nlmixr2autoinit rxode2 dplyr progressr processx withr crayon

LinkingTo (0)

none

Suggests (0)

none

Enhances (0)

none

Dependencies facing archival

CRAN will archive these unless their check problems are fixed by the date shown. This package needs each one to install.

nlmixr2estfix by Oct 23
nlmixr2plot through nlmixr2fix by Oct 22

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Suggested by 1

Suggests, most downloaded first

nlmixr2

How these are counted

Code & Tests

People & History

People (4)

Zhonghui Huang

Author, Maintainer since 1.0.0 (2026)

Matthew Fidler

Contributor

Frank Kloprogge

Contributor

Joseph Standing

Contributor

Releases (1)

R
R 4.6.0 released · 2026-04-24
1.0.0Latest
record
2026-02-06 · current release
R
R 4.5.0 released · 2025-04-11

Package metadata

First published: 2026-02-06
Total releases: 1 / 1 yrs
License: GPL (>= 3) OSI
Minimum R: ≥ 4.1.0
Download size: 107 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("nlmixr2auto")

Format

Huang, Z., Fidler, M., Kloprogge, F., & Standing, J. (2026). nlmixr2auto: Automated Population Pharmacokinetic Modeling (Version 1.0.0) [Computer software]. https://doi.org/10.32614/CRAN.package.nlmixr2auto

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for nlmixr2auto version 1.0.0 [Data set]. HJJB, LLC. Data release v2026-10-17. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-17, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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