Toolkit of Helper Functions to Pre-Process Amplification Data
Overview
A collection of functions to pre-process amplification curve data from polymerase chain reaction (PCR) or isothermal amplification reactions. Contains functions to normalize and baseline amplification curves, to detect both the start and end of an amplification reaction, several smoothers (e.g., LOWESS, moving average, cubic splines, Savitzky-Golay), a function to detect false positive amplification reactions and a function to determine the amplification efficiency. Quantification point (Cq) methods include the first (FDM) and second approximate derivative maximum (SDM) methods (calculated by a 5-point-stencil) and the cycle threshold method. Data sets of experimental nucleic acid amplification systems ('VideoScan HCU', capillary convective PCR (ccPCR)) and commercial systems are included. Amplification curves were generated by helicase dependent amplification (HDA), ccPCR or PCR. As detection system intercalating dyes (EvaGreen, SYBR Green) and hydrolysis probes (TaqMan) were used. For more information see: Roediger et al. (2015) doi:10.1093/bioinformatics/btv205.
Install
Health
NOTERd filesr-devel-linux-x86_64-debian-clang, r-devel-linux-x86_64-debian-gcc, r-devel-linux-x86_64-fedora-clang, r-devel-linux-x86_64-fedora-gcc, r-devel-windows-x86_64, r-oldrel-macos-arm64, r-oldrel-macos-x86_64, r-oldrel-windows-x86_64, r-patched-linux-x86_64, r-release-linux-x86_64, r-release-macos-arm64, r-release-macos-x86_64, r-release-windows-x86_64
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Maintainer: ‘Stefan Roediger <stefan.roediger@b-tu.de>’ Package CITATION file contains call(s) to old-style citEntry(). Please use bibentry() instead.
- NOTE13 NOTENow
- NOTE14 NOTE2026-03-10
Documentation
- Help pages
- 64includes a package overview page
- Examples that run
- 95%57 run in a plain check · 3 never run
- Exported functions with examples
- 94%
- Documented parameters
- 94%
- Return-value docs
- 89%
- Help pages citing references
- 69%
Downloads
Repository
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6 development-tooling and community-health practices detected across 3 families in the upstream repository
Checks run against github.com/pcruniversum/chippcr on 2026-10-25.
The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel
GitHub Pages site last deployed 2021-02-27 · The repository has a site deploy workflow
Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- unarchivedReturned to CRAN2021-03-05
- 1.0-2Latest
- archivedRemoved from CRAN2020-12-16mail to the maintainer bounced
- RR 4.0.0 released · 2020-04-24
- RR 3.6.0 released · 2019-04-26
- RR 3.5.0 released · 2018-04-23
- RR 3.4.0 released · 2017-04-21
- RR 3.3.0 released · 2016-05-03
- RR 3.2.0 released · 2015-04-16
- 0.0.8-102015-04-10 · diff ↗
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- 0.0.8-82015-03-12 · diff ↗
- 0.0.8-62015-02-23 · diff ↗
- 0.0.8-32014-09-29 · diff ↗
- 0.0.8-12014-08-26 · diff ↗ ·
added 7 exports
amptester.gui, humanrater, lm.coefs, MFIaggr.gui, normalizer, plotCurves, th.cyc - 0.0.7
- 0.0.62014-04-24 · diff ↗
- RR 3.1.0 released · 2014-04-10
- 0.0.52013-12-12
- RR 3.0.0 released · 2013-04-03
Package metadata
- First published
- 2013-12-12
- Total releases
- 9 / 13 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 3.0.0
- Bundled data
- 1.9 MB / 32 files
- Download size
- 2.3 MB
Cite
Cite this package
Run in R for the authors' entry:
citation("chipPCR")The package provides a citation file, so citation() returns the authors' own entry.
It points to 10.1093/bioinformatics/btv205.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-26, which the citation names so these numbers can be found later. More on citing and the projects behind them.