bfboinet
1.1.0Backfill Bayesian Optimal Interval Design Using Efficacy and Toxicity
Overview
Implements the Backfill Bayesian Optimal Interval Design (BF-BOIN-ET), a novel clinical trial methodology for dose optimization that simultaneously consider both efficacy and toxicity outcome as described in (Takeda et al (2025) doi:10.1002/pst.2470). The package has been extended to include a seamless two-stage phase I/II trial design with backfill and joint efficacy and toxicity monitoring as described in (Takeda et al (2026) doi:10.1002/pst.70092).
Install
Health
- OK2026-08-0513 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- NOTE2026-08-0112 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- OK2026-06-0913 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- ERROR2026-06-0812 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
- OK2026-03-1014 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Documentation
- Examples that run
- 100%
- Documented parameters
- 100%
- Return-value docs
- 100%
- References docs
- 100%
Downloads
Dependencies
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Code & Tests
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Package metadata
- First published
- 2024-11-18
- Total releases
- 6 / 2 yrs
- License
- GPL-3 OSI
- Download size
- 40 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet
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