Generalized UniFrac Distances, Distance-Based Multivariate Methods and Feature-Based Univariate Methods for Microbiome Data Analysis
Overview
A suite of methods for powerful and robust microbiome data analysis including data normalization, data simulation, community-level association testing and differential abundance analysis. It implements generalized UniFrac distances, Geometric Mean of Pairwise Ratios (GMPR) normalization, semiparametric data simulator, distance-based statistical methods, and feature-based statistical methods. The distance-based statistical methods include three extensions of PERMANOVA: (1) PERMANOVA using the Freedman-Lane permutation scheme, (2) PERMANOVA omnibus test using multiple matrices, and (3) analytical approach to approximating PERMANOVA p-value. Feature-based statistical methods include linear model-based methods for differential abundance analysis of zero-inflated high-dimensional compositional data.
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK14 OK2026-04-22
- ERROR13 OK, 1 ERROR2026-04-18
- OK14 OK2026-03-10
Documentation
- Help pages
- 19
- Examples that run
- 74%14 run in a plain check · 5 never run
- Exported functions with examples
- 100%
- Documented parameters
- 93%
- Return-value docs
- 100%
- Help pages citing references
- 74%
Downloads
Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- 1.9Latest
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- 1.82023-09-14 · diff ↗
- RR 4.3.0 released · 2023-04-21
- 1.7
- 1.6
- RR 4.2.0 released · 2022-04-22
- 1.5
- 1.4
- 1.3
- RR 4.1.0 released · 2021-05-18
- 1.22021-05-03 · diff ↗ ·
removed 1 export
pattern:^[[:alpha:]]+added 6 exports
GUniFrac, Rarefy, PermanovaG, PermanovaG2, dmanova, adonis3 - RR 4.0.0 released · 2020-04-24
- RR 3.6.0 released · 2019-04-26
Show 11 earlier eventsHide 11 earlier events
- RR 3.5.0 released · 2018-04-23
- 1.1
- unarchivedReturned to CRAN2018-02-12
- RR 3.4.0 released · 2017-04-21
- RR 3.3.0 released · 2016-05-03
- RR 3.2.0 released · 2015-04-16
- orphanedOrphaned by its maintainer2014-12-07maintainer address <chenjun@mail.med.upenn.edu> bounced
- RR 3.1.0 released · 2014-04-10
- RR 3.0.0 released · 2013-04-03
- 1.02012-04-28
- RR 2.15.0 released · 2012-03-30
Package metadata
- First published
- 2012-04-28
- Total releases
- 10 / 14 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 3.5.0
- Bundled data
- 263 KB / 5 files
- Download size
- 823 KB
Cite
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citation("GUniFrac")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
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