Skip to content

miQC

Bioc current

Flexible, probabilistic metrics for quality control of scRNA-seq data

v1.20.0 · software · BSD_3_clause + file LICENSE

Release Lineage

Entered 3.13 · May 20, 2021

Current · Requires R 4.6

1.0 In 11 of 49 releases 3.23

Description

Single-cell RNA-sequencing (scRNA-seq) has made it possible to profile gene expression in tissues at high resolution. An important preprocessing step prior to performing downstream analyses is to identify and remove cells with poor or degraded sample quality using quality control (QC) metrics. Two widely used QC metrics to identify a ‘low-quality’ cell are (i) if the cell includes a high proportion of reads that map to mitochondrial DNA encoded genes (mtDNA) and (ii) if a small number of genes are detected. miQC is data-driven QC metric that jointly models both the proportion of reads mapping to mtDNA and the number of detected genes with mixture models in a probabilistic framework to predict the low-quality cells in a given dataset.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

6 6 exported

Complexity

4.3 avg / 7 max

Call network

6 nodes / 4 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

1,225

Files

23

Compiled share

0%

Has compiled src

No

Language breakdown

R 525 (42.9%)Docs 355 (29%)Vignettes 345 (28.2%)

API

Exported functions

6

Internal functions

0

Testing & CI

Has tests

No

Test-to-code ratio

0.00

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

System requirements

C++ standard

License

BSD_3_clause + file LICENSE

License flags

SPDX valid, OSI approved

History

Versions

11

First release

2021-05-19

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

Dep drift

1

LOC over versions

v3.13: 845 LOCv3.14: 1,068 LOCv3.15: 1,068 LOCv3.16: 1,090 LOCv3.17: 1,225 LOCv3.18: 1,225 LOCv3.19: 1,225 LOCv3.20: 1,225 LOCv3.21: 1,225 LOCv3.22: 1,225 LOCv3.23: 1,225 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 154 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 67% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
100%
Return-value docs
100%
References docs
0%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("miQC")
Hippen, A., & Hicks, S. (2026). miQC: Flexible, probabilistic metrics for quality control of scRNA-seq data (Version 1.20.0) [Computer software]. https://bioconductor.org/packages/miQC

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for miQC version 1.20.0 [Data set]. HJJB, LLC. Data release v2026-08-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

Report a problem with this page →

Privacy choices

These apply to this browser and are stored on this device only. Nothing about your choice is sent to us.

Read the privacy policy