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gCrisprTools

Bioc current

Suite of Functions for Pooled Crispr Screen QC and Analysis

v2.18.0 · software · Artistic-2.0

Release Lineage

Entered 3.4 · Oct 18, 2016

Current · Requires R 4.6

1.0 In 20 of 49 releases 3.23

Description

Set of tools for evaluating pooled high-throughput screening experiments, typically employing CRISPR/Cas9 or shRNA expression cassettes. Contains methods for interrogating library and cassette behavior within an experiment, identifying differentially abundant cassettes, aggregating signals to identify candidate targets for empirical validation, hypothesis testing, and comprehensive reporting. Version 2.0 extends these applications to include a variety of tools for contextualizing and integrating signals across many experiments, incorporates extended signal enrichment methodologies via the "sparrow" package, and streamlines many formal requirements to aid in interpretablity.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

64 51 exported

Complexity

5.5 avg / 18 max

Call network

64 nodes / 88 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

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Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

8,189

Files

124

Compiled share

0%

Has compiled src

No

Language breakdown

R 4,514 (55.1%)Tests 2 (0%)Docs 2,813 (34.4%)Vignettes 860 (10.5%)

API

Exported functions

51

Internal functions

13

Recent export changes

v3.5+2 ct.applyAlpha, ct.makeRhoNull

Testing & CI

Has tests

Yes

Test-to-code ratio

0.00

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

50%

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.1

System requirements

C++ standard

License

Artistic-2.0

License flags

SPDX valid, OSI approved

History

Versions

20

First release

2016-10-17

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

100%

Dep drift

10

LOC over versions

v3.4: 6,557 LOCv3.5: 5,797 LOCv3.6: 5,816 LOCv3.7: 5,816 LOCv3.8: 5,831 LOCv3.9: 5,820 LOCv3.10: 5,820 LOCv3.11: 6,871 LOCv3.12: 6,871 LOCv3.13: 6,871 LOCv3.14: 8,146 LOCv3.15: 8,139 LOCv3.16: 8,133 LOCv3.17: 8,133 LOCv3.18: 8,133 LOCv3.19: 8,133 LOCv3.20: 8,133 LOCv3.21: 8,133 LOCv3.22: 8,133 LOCv3.23: 8,189 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 61 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 67% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
98%
Return-value docs
100%
References docs
0%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("gCrisprTools")
Bainer, R., Genentech, Inc., Light Horse Therapeutics, Maze Therapeutics, Haverty, P., Lianoglou, S., & Ratman, D. (2026). gCrisprTools: Suite of Functions for Pooled Crispr Screen QC and Analysis (Version 2.18.0) [Computer software]. https://bioconductor.org/packages/gCrisprTools

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for gCrisprTools version 2.18.0 [Data set]. HJJB, LLC. Data release v2026-08-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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