G4SNVHunter
Bioc currentEvaluating SNV-Induced Disruption of G-Quadruplex Structures
Release Lineage
Entered 3.21 · Apr 16, 2025
Current · Requires R 4.6
Description
G-quadruplexes (G4s) are unique nucleic acid secondary structures predominantly found in guanine-rich regions and have been shown to be involved in various biological regulatory processes. G4SNVHunter is an R package designed to rapidly identify genomic sequences with G4-forming propensity and to accurately screen user-provided single nucleotide variants—as well as other small-scale variants such as indels and MNVs—for their potential to destabilize these structures. This allows researchers to then screen these critical variants for deeper study, digging into how they might influence biological functions—think gene regulation, for instance—by impairing G4 formation propensity.
Test coverage
Line coverage
–
Expression
–
Tests / Examples
–
Functions
43 16 exported
Complexity
6.9 avg / 24 max
Call network
43 nodes / 31 edges
Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.
Call graph
Open call graph →Lowest coverage
Per-function coverage is not measured for this package yet.
Code
Structure
Lines of code
5,753
Files
84
Compiled share
1.1%
Has compiled src
Yes
Language breakdown
API
Exported functions
16
Internal functions
23
Recent export changes
Testing & CI
Has tests
Yes
Test-to-code ratio
0.23
testthat edition
3
CI present
No
CI type
[]
PR gated
No
Docs
Roxygen coverage
100%
Health & Security signals
Informational signals; not verdicts.
on.exit coverage
–
Unsafe pattern score
0
Dep constraint coverage
0%
Secret pattern count
0
Bundled 3rd-party code
2 items
Portability & License
Min R version
4.3.0
System requirements
–
C++ standard
C++11
License
MIT + file LICENSE
License flags
SPDX valid, OSI approved
History
Versions
3
First release
2025-04-15
Latest release
2026-04-28
Avg cadence
189 days
Cold removal rate
–
Dep drift
10
LOC over versions
Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.
Documentation
- Examples that run
- 100%
- Documented parameters
- 92%
- Return-value docs
- 100%
- References docs
- 0%
Topics
People
- Rongxin Zhang maintainer author
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("G4SNVHunter")This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-08-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.