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tigger

1.2.0

Infers Novel Immunoglobulin Alleles from Sequencing Data

2packages depend
8Kdownloads / year
–test coverage
13/13flavors OK

Overview

About

Infers the V genotype of an individual from immunoglobulin (Ig) repertoire sequencing data (AIRR-Seq, Rep-Seq). Includes detection of any novel alleles. This information is then used to correct existing V allele calls from among the sample sequences. Citations: Gadala-Maria, et al (2015) doi:10.1073/pnas.1417683112, Gadala-Maria, et al (2019) doi:10.3389/fimmu.2019.00129.

Changes in 1.2.0

General:

  • Updated dependencies to alakazam >= 1.5.0.

New Features:

  • Added the function plotGenotypeConfidence, which draws a genotype next to a color panel showing a per-gene confidence value, such as the k_diff returned by inferGenotypeBayesian.
  • Added the genotyped_alleles argument to inferGenotypeBayesian. When TRUE, a genotyped_alleles column is added with the most likely alleles based on the highest Bayesian zygosity likelihood.
  • Added the allele_col argument to plotGenotype to choose the column of alleles to plot (e.g., allele_col="genotyped_alleles").
  • Added the include_unseen and strip_d arguments to genotypeFasta. With include_unseen=TRUE, germline alleles of genes absent from the genotype are also returned. genotypeFasta now uses the genotyped_alleles column, when present, instead of alleles.
Show all changes in 1.2.0Hide the rest of the changes in 1.2.0
  • Added the trim_seq, overwrite, ignored_regex, treat_multigene_as_uncalled, top_k, top_by, strip_d and reassign_uncalled arguments to reassignAlleles.
  • reassignAlleles now supports D and J calls. The segment is determined from the prefix of the v_call argument, and the result is written to the v_call_genotyped, d_call_genotyped or j_call_genotyped column accordingly. The v_call column name must now begin with v, d or j.

Backwards Incompatible Changes:

  • When gene_cutoff is a fraction, inferGenotype now computes the cutoff from the number of sequences of the gene's locus instead of the whole repertoire. inferGenotype and inferGenotypeBayesian warn when calls from more than one locus are detected.

Bug Fixes:

  • Fixed reassignAlleles not realigning sequences when only one sequence had a gene absent from the genotype.

Performance:

  • reassignAlleles now uses alakazam::seqMismatchMatrix and alakazam::seqMismatchCount to compute Hamming distances, and parses allele calls only once per unique call.

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 10.8 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-04
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-06-09
  • ERROR12 OK, 1 ERROR2026-06-08
  • OK13 OK2026-05-10
Show 4 earlier changesHide 4 earlier changes
  • ERROR12 OK, 1 ERROR2026-05-03
  • OK12 OK2026-04-25
  • ERROR13 OK, 1 ERROR2026-03-30
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 1.2.0
READMEYes · 301 wordsVignettesYes · 1 · dynamicNEWSYes · 100% structured · mentions 1.2.0Citation fileYes · cites a publicationWebsiteYes
Help pages
29 (1 internal)includes a package overview page
Examples that run
81%17 run in a plain check · 2 only when donttest examples are enabled (R CMD check --as-cran) · 2 hold no code
Exported functions with examples
100%
Documented parameters
99%
Return-value docs
95%
Help pages citing references
31%

Downloads

8K
CRAN downloads in the past year
Rank #4,197 · ~22/day · ~667/mo
Daily download trend is not available in this view yet.
92430 days
2.1K90 days
8K1 year
Compare downloads with other packages →
Also on182 r2u8 autocran3.7K conda_forge334 bioconda

Repository

1Stars
1Forks
5Open issues
0Open PRs
0Releases
648Commits
11Commit identities
License file reads as AGPL-3.0 · 648 commits · Last activity 2026-10-09 · Default branch at 1.2.0.999, ahead of CRAN 1.2.0 (checked 2026-10-11)
Responsiveness
How these are sampled
PRs merged (all time)
100%
Median days to close, 50 most recently updated closed issues
10
Median days to close, 50 most recently updated closed PRs
1

Stars over time

2026-07-07 · 02026-10-15 · 1
PracticesBeta

4 development-tooling and community-health practices detected across 2 families in the upstream repository

Checks run against github.com/immcantation/tigger on 2026-10-11.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux

Governance and community (2)
Code of conduct (inherited from immcantation)Contributing guide
How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies
15 external dependencies (excludes base and recommended)

Installing tigger adds 59 packages (33 with compiled code, 55 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, igraph 4.8 MB. 3 more not on CRAN are not measured.

Depends (2)
R >= 4.0ggplot2
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
2direct
0indirect
Imports 2
Depends, Imports or LinkingTo, most downloaded first

Datasets

People & History

People (7)
Author, Maintainer since 1.0.1 (2022) · added in 0.3.0
Author · added in 0.3.0
Author, Copyright holder
Author · added in 1.1.3
Author · added in 0.3.0

Previously maintained by Jason Vander Heiden (0.2.10 to 1.0.0) and Daniel Gadala-Maria (0.2.5 to 0.2.9.999).

Releases (15)

Pick two releases to compare their code metrics.

  • 1.2.0Latest
    record
    2026-10-06 · current release · diff ↗ ·
    added 1 export
    plotGenotypeConfidence
  • R
    R 4.6.0 released · 2026-04-24
  • 1.1.3
    record
    2026-04-17 · diff ↗
  • 1.1.2
    record
    2026-01-10 · diff ↗
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • 1.1.0
    record
    2023-10-10 · diff ↗
  • R
    R 4.3.0 released · 2023-04-21
  • 1.0.1
    record
    2022-09-20 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • 1.0.0
    record
    2020-05-13 · diff ↗ ·
    added 1 export
    subsampleDb
  • R
    R 4.0.0 released · 2020-04-24
  • 0.4.0
    record
    2019-07-19 · diff ↗
  • R
    R 3.6.0 released · 2019-04-26
  • 0.3.1
    record
    2018-10-19 · diff ↗
Show 10 earlier eventsHide 10 earlier events

Package metadata

First published
2016-06-08
Total releases
15 / 10 yrs
License
AGPL-3 OSI · relicensed from CC BY-SA 4.0 in 1.0.0
Minimum R
≥ 4.0
Bundled data
2.5 MB / 6 files
Download size
2.7 MB

Cite

Cite this package

Run in R for the authors' entry:

citation("tigger")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.1073/pnas.1417683112, 10.3389/fimmu.2019.00129.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for tigger version 1.2.0 [Data set]. HJJB, LLC. Data release v2026-10-17. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-17, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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