Interpretation of Heterogeneous Single-Cell Gene Expression Data
Overview
We develop a novel matrix factorization tool named 'scINSIGHT' to jointly analyze multiple single-cell gene expression samples from biologically heterogeneous sources, such as different disease phases, treatment groups, or developmental stages. Given multiple gene expression samples from different biological conditions, 'scINSIGHT' simultaneously identifies common and condition-specific gene modules and quantify their expression levels in each sample in a lower-dimensional space. With the factorized results, the inferred expression levels and memberships of common gene modules can be used to cluster cells and detect cell identities, and the condition-specific gene modules can help compare functional differences in transcriptomes from distinct conditions. Please also see Qian K, Fu SW, Li HW, Li WV (2022) doi:10.1186/s13059-022-02649-3.
Install
Health
- OK13 OK2026-08-04
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
- WARNING12 OK, 1 WARNING2026-06-08
- OK13 OK2026-05-02
Show 6 earlier changesHide 6 earlier changes
- NOTE11 OK, 1 NOTE2026-04-25
- OK14 OK2026-04-22
- ERROR13 OK, 1 ERROR2026-04-18
- OK14 OK2026-04-16
- NOTE13 OK, 1 NOTE2026-03-28
- OK14 OK2026-03-10
Documentation
- Help pages
- 3
- Examples that run
- 100%1 run in a plain check
- Exported functions with examples
- 50%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 0%
Downloads
Repository
- PRs merged (all time)
- not measured
- Median days to close, 50 most recently updated closed issues
- 8
- Median days to close, 50 most recently updated closed PRs
- not measured
Stars over time
Forks over time
Issues over time
2 development-tooling and community-health practices detected across 2 families in the upstream repository
Checks run against github.com/vivianstats/scinsight on 2026-10-21.
Dependencies
Code & Tests
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- 0.1.5Latest
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- 0.1.42022-05-30 · diff ↗
- RR 4.2.0 released · 2022-04-22
- 0.1.32022-02-03 · diff ↗
- 0.1.22022-01-24 · diff ↗
- 0.1.12021-09-06 · diff ↗
- RR 4.1.0 released · 2021-05-18
- 0.1.02021-05-03
- RR 4.0.0 released · 2020-04-24
Package metadata
- First published
- 2021-05-03
- Total releases
- 6 / 5 yrs
- License
- GPL-3 OSI
- Download size
- 15 KB
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("scINSIGHT")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-25, which the citation names so these numbers can be found later. More on citing and the projects behind them.