R Observatory: Metrics for replicateBE version 1.1.3

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

replicateBE

1.1.3Package record

Average Bioequivalence with Expanding Limits (ABEL)

0packages depend

3.6Kdownloads / year

37.2%test coverage

0/13flavors OK

Overview

About

Maintained by Helmut SchützCRAN page ↗GitHub ↗Issues ↗

Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well.

Changes in 1.1.3

Published on GitHub 2022-05-02.

Bug fixes

Fixed two more empty item{} discovered by CRAN pretest.

From NEWS.md in the release

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("replicateBE", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("Helmut01/replicateBE")

Development version from Helmut01/replicateBE. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-replicatebe

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled. We list this channel from recorded r2u download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-replicateBE

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-replicateBE

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed). We list this channel from recorded autoCRAN download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

Health

CRAN checks

13NOTE

Check messages

NOTERd filesr-devel-linux-x86_64-debian-clang, r-devel-linux-x86_64-debian-gcc, r-devel-linux-x86_64-fedora-clang, r-devel-linux-x86_64-fedora-gcc, r-devel-windows-x86_64, r-oldrel-macos-arm64, r-oldrel-macos-x86_64, r-oldrel-windows-x86_64, r-patched-linux-x86_64, r-release-linux-x86_64, r-release-macos-arm64, r-release-macos-x86_64, r-release-windows-x86_64

checkRd: (-1) method.A.Rd:200-205: Lost braces in \itemize; \value handles \item{}{} directly
checkRd: (-1) method.A.Rd:206-211: Lost braces in \itemize; \value handles \item{}{} directly
checkRd: (-1) method.A.Rd:231-236: Lost braces in \itemize; \value handles \item{}{} directly
checkRd: (-1) method.A.Rd:237-242: Lost braces in \itemize; \value handles \item{}{} directly
checkRd: (-1) method.B.Rd:201-206: Lost braces in \itemize; \value handles \item{}{} directly
checkRd: (-1) method.B.Rd:207-212: Lost braces in \itemize; \value handles \item{}{} directly
checkRd: (-1) method.B.Rd:232-237: Lost braces in \itemize; \value handles \item{}{} directly
checkRd: (-1) method.B.Rd:238-243: Lost braces in \itemize; \value handles \item{}{} directly

CRAN check page ↗

Slowest check: 4.1 min · r-oldrel-windows-x86_64

Status changes

NOTE13 NOTE2026-06-09
ERROR12 NOTE, 1 ERROR2026-06-08
NOTE14 NOTE2026-03-10

Advisories

none known

How this is measured·How advisories are found

Documentation

In release 1.1.3

READMEYes · 1,607 wordsVignettesYes · 1 · dynamicNEWSYes · 100% structured · mentions 1.1.3Citation fileNoWebsitenot declared in DESCRIPTION

Help pages: 14
Examples that run: 100%14 run in a plain check
Exported functions with examples: 100%
Documented parameters: 100%
Return-value docs: 100%
Help pages citing references: 71%

Vignettes (1)

replicateBE

How these are measured

Downloads

3.6K

CRAN downloads in the past year

Rank #11,078 · ~10/day · ~301/mo

Releases R versions

Daily download trend is not available in this view yet.

36330 days

94490 days

3.6K1 year

Compare downloads with other packages →

Also on92 r2u9 autocran79 c2d4u

How downloads are counted

Repository

helmut01/replicatebe ↗Account: Helmut01

10Stars

4Forks

3Open issues

0Open PRs

11Releases

357Commits

2Commit identities

bioequivalencebiostatisticsrr-packagerstats

357 commits · Last activity 2022-05-04 · 0% stars, 30d · Default branch at 1.1.3.9000, ahead of CRAN 1.1.3 (checked 2026-10-11)

Responsiveness

How these are sampled

PRs merged (all time): not measured
Median days to close, 50 most recently updated closed issues: 1
Median days to close, 50 most recently updated closed PRs: not measured

Stars over time

2023-02-19 · 82026-07-07 · 10

How these are measured

PracticesBeta

1 development-tooling and community-health practice detected across 1 family in the upstream repository

Checks run against github.com/helmut01/replicatebe on 2026-10-11.

Docs source (1)

README.Rmd

How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies

8 external dependencies (excludes base and recommended)

Installing replicateBE adds 64 packages (33 with compiled code, 60 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, doBy 4.3 MB.

Depends (1)

R >= 3.5.0

Imports (7)

readxl PowerTOST lmerTestnlmepbkrtestgraphicsgrDevices

LinkingTo (0)

none

Suggests (4)

knitr rmarkdown testthat devtools

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

How these are counted

Code & Tests

Datasets

People & History

People (3)

Helmut Schütz

Author, Maintainer since 1.0.7 (2019)

Detlew Labes

Contributor

Michael Tomashevskiy

Contributor

Releases (13)

Pick two releases to compare their code metrics.

R
R 4.6.0 released · 2026-04-24
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R 4.5.0 released · 2025-04-11
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R 4.4.0 released · 2024-04-24
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R 4.3.0 released · 2023-04-21
1.1.3Latest
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2022-05-03 · current release · diff ↗
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R 4.2.0 released · 2022-04-22
1.1.1
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2022-02-13 · diff ↗
1.1.0
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2021-06-21 · diff ↗
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R 4.1.0 released · 2021-05-18
1.0.17
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2021-05-14 · diff ↗
1.0.15
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2020-07-24 · diff ↗
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R 4.0.0 released · 2020-04-24
1.0.14
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2020-04-09 · diff ↗
1.0.13
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2020-01-09 · diff ↗
1.0.12
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2019-11-11 · diff ↗
1.0.11
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2019-08-25 · diff ↗

Show 5 earlier eventsHide 5 earlier events

1.0.10
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2019-07-24 · diff ↗
1.0.9
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2019-07-22 · diff ↗
1.0.8
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2019-06-14 · diff ↗
1.0.7
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2019-06-14
R
R 3.6.0 released · 2019-04-26

Package metadata

First published: 2019-06-14
Total releases: 13 / 7 yrs
License: GPL (>= 3) OSI
Minimum R: ≥ 3.5.0
Bundled data: 53 KB / 10 files
Download size: 291 KB

Appears in task views

Clinical Trial Design, Monitoring, Analysis and Reporting Analysis of Pharmacokinetic Data

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("replicateBE")

Format

Schütz, H., Labes, D., & Tomashevskiy, M. (2022). replicateBE: Average Bioequivalence with Expanding Limits (ABEL) (Version 1.1.3) [Computer software]. https://doi.org/10.32614/CRAN.package.replicateBE

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for replicateBE version 1.1.3 [Data set]. HJJB, LLC. Data release v2026-10-19. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-19, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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