R Observatory: Metrics for replicateBE version 1.1.3

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

replicateBE

1.1.3

Average Bioequivalence with Expanding Limits (ABEL)

0packages depend

3.5Kdownloads / year

37.2%test coverage

0/13checks pass

Overview

About

Maintained by Helmut SchützFirst published 2019-06-1413 releasesCRAN page ↗GitHub ↗

Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well.

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("replicateBE", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("Helmut01/replicateBE")

Development version from Helmut01/replicateBE. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-replicatebe

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-replicateBE

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-replicateBE

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

13NOTE

Failing flavors

NOTE r-devel-linux-x86_64-debian-clang
NOTE r-devel-linux-x86_64-debian-gcc
NOTE r-devel-linux-x86_64-fedora-clang
NOTE r-devel-linux-x86_64-fedora-gcc
NOTE r-devel-windows-x86_64
NOTE r-oldrel-macos-arm64
NOTE r-oldrel-macos-x86_64
NOTE r-oldrel-windows-x86_64
NOTE r-patched-linux-x86_64
NOTE r-release-linux-x86_64
NOTE r-release-macos-arm64
NOTE r-release-macos-x86_64
NOTE r-release-windows-x86_64

Slowest check: 4.1 min · r-oldrel-windows-x86_64

Code health

Yes

Tests · ratio 0.29

37.2%

Coverage · measured lines

100%

Documentation · exports

7

Dependencies · direct

Check history

NOTE2026-06-09
0 OK · 13 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-06-08
0 OK · 12 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
NOTE2026-03-10
0 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMEYes · 1,607 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo

Examples that run: 100%
Documented parameters: 100%
Return-value docs: 100%
References docs: 71%

Downloads

3.5K

CRAN downloads in the past year

Rank #11,572 · ~10/day · ~290/mo

Releases R versions

Daily download trend is not available in this view yet.

20230 days

85290 days

3.5K1 year

Compare downloads with other packages →

Also on121 r2u20 autocran38 c2d4u

Repository

GitHub ↗ helmut01/replicatebe

10Stars

4Forks

3Open issues

0Open PRs

11Releases

357Commits

2Contributors

bioequivalencebiostatisticsrr-packagerstats

357 commits · Last activity 2022-05-04 · 0% stars, 30d

Stars over time

2023-02-19 · 82026-07-07 · 10

Repository practices

Upstream repositoryBeta

1 development-tooling and community-health practice detected across 1 family in the upstream repository

Checks run against github.com/helmut01/replicatebe on 2026-08-16.

Docs source (1)

README.Rmd

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

8 external dependencies (excludes base and recommended)

Depends (1)

R >= 3.5.0

Imports (7)

readxl PowerTOST lmerTestnlmepbkrtestgraphicsgrDevices

LinkingTo (0)

none

Suggests (4)

knitr rmarkdown testthat devtools

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

Datasets

People & History

People (3)

Maintainer (1)

Helmut Schütz

Author, Maintainer

Authors (1)

Helmut Schütz

Author, Maintainer

Contributors (2)

Detlew Labes

Contributor

Michael Tomashevskiy

Contributor

Package Timeline

13 releases. Pick two to compare their code metrics. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
R
R 4.5.0 released · 2025-04-11
R
R 4.4.0 released · 2024-04-24
R
R 4.3.0 released · 2023-04-21
1.1.3Latest
2022-05-03 · current release · diff ↗
R
R 4.2.0 released · 2022-04-22
1.1.1
2022-02-13 · diff ↗
1.1.0
2021-06-21 · diff ↗
R
R 4.1.0 released · 2021-05-18
1.0.17
2021-05-14 · diff ↗
1.0.15
2020-07-24 · diff ↗
R
R 4.0.0 released · 2020-04-24
1.0.14
2020-04-09 · diff ↗
1.0.13
2020-01-09 · diff ↗
1.0.12
2019-11-11 · diff ↗
1.0.11
2019-08-25 · diff ↗

Show 5 earlier events

1.0.10
2019-07-24 · diff ↗
1.0.9
2019-07-22 · diff ↗
1.0.8
2019-06-14 · diff ↗
1.0.7
2019-06-14
R
R 3.6.0 released · 2019-04-26

Package metadata

First published: 2019-06-14
Total releases: 13 / 7 yrs
License: GPL (>= 3) OSI
Minimum R: ≥ 3.5.0
Bundled data: 53 KB / 10 files
Download size: 291 KB
Installed size: not tracked yet
With dependencies: not tracked yet

Appears in task views

Clinical Trial Design, Monitoring, Analysis and Reporting Analysis of Pharmacokinetic Data

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("replicateBE")

Format

Schütz, H., Labes, D., & Tomashevskiy, M. (2022). replicateBE: Average Bioequivalence with Expanding Limits (ABEL) (Version 1.1.3) [Computer software]. https://doi.org/10.32614/CRAN.package.replicateBE

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for replicateBE version 1.1.3 [Data set]. HJJB, LLC. Data release v2026-08-18. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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