R Observatory: Metrics for posologyr version 1.2.8

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

posologyr

1.2.8Package record

Individual Dose Optimization using Population Pharmacokinetics

0packages dependsuggested by 1

4.3Kdownloads / year

69.4%test coverage

13/13flavors OK

Overview

About

Maintained by Cyril LevenCRAN page ↗GitHub ↗Website ↗Issues ↗

Personalize drug regimens using individual pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) profiles. By combining therapeutic drug monitoring (TDM) data with a population model, 'posologyr' offers accurate posterior estimates and helps compute optimal individualized dosing regimens. The empirical Bayes estimates are computed following the method described by Kang et al. (2012) doi:10.4196/kjpp.2012.16.2.97.

Changes in 1.2.8

Relax the requirements of a dose optimization test using TDM data to account for computational differences observed with the alternative BLAS ATLAS on CRAN.

From NEWS.md in the release

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("posologyr", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("levenc/posologyr")

Development version from levenc/posologyr. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-posologyr

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled. We list this channel from recorded r2u download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-posologyr

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-posologyr

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed). We list this channel from recorded autoCRAN download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

Health

CRAN checks

13OK

CRAN check page ↗

Slowest check: 43.3 min · r-oldrel-windows-x86_64

Status changes

OK13 OK2026-10-18
ERROR12 OK, 1 ERROR2026-10-11
OK13 OK2026-10-03
ERROR12 OK, 1 ERROR2026-09-11
OK13 OK2026-08-28

Show 7 earlier changesHide 7 earlier changes

ERROR12 OK, 1 ERROR2026-08-26
OK13 OK2026-08-12
ERROR10 OK, 1 NOTE, 2 ERROR2026-08-04
NOTE12 OK, 1 NOTE2026-08-01
OK12 OK, 1 FAILURE2026-06-09
ERROR12 OK, 1 ERROR2026-06-08
OK14 OK2026-03-10

Advisories

none known

How this is measured·How advisories are found

Documentation

In release 1.2.8

READMEYes · 399 wordsVignettesNoNEWSYes · 100% structured · mentions 1.2.8Citation fileYes · cites a publicationWebsiteYes · pkgdown

The repository also keeps web-only articles.

Help pages: 10 (1 internal)
Examples that run: 100%9 run in a plain check
Exported functions with examples: 90%
Documented parameters: 97%
Return-value docs: 100%
Help pages citing references: 10%

How these are measured

Downloads

4.3K

CRAN downloads in the past year

Rank #5,913 · ~12/day · ~359/mo

Releases R versions

Daily download trend is not available in this view yet.

53530 days

1.4K90 days

4.3K1 year

Compare downloads with other packages →

Also on68 r2u11 autocran33 c2d4u

How downloads are counted

Repository

levenc/posologyr ↗Account: levenc

16Stars

2Forks

2Open issues

0Open PRs

10Releases

374Commits

2Commit identities

pharmacokineticstherapeutic-drug-monitoringbayesianprecision-medicinemodel-informed-precision-dosing

License file reads as AGPL-3.0 · 374 commits · Last activity 2026-04-10 · 0% stars, 30d · Default branch at 1.2.8.999, ahead of CRAN 1.2.8 (checked 2026-10-11)

Responsiveness

How these are sampled

PRs merged (all time): 100%
Median days to close, 50 most recently updated closed issues: 2
Median days to close, 50 most recently updated closed PRs: 0

Stars over time

2025-07-22 · 152026-07-07 · 16

How these are measured

PracticesBeta

5 development-tooling and community-health practices detected across 2 families in the upstream repository

Checks run against github.com/levenc/posologyr on 2026-10-11.

Continuous integration (2)

GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (3)

README.Rmdpkgdown

GitHub Pages site last deployed 2026-04-10

pkgdown site last built 2026-03-31

How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies

9 external dependencies (excludes base and recommended)

Installing posologyr adds 48 packages (30 with compiled code, 53 MB of source tarballs). Heaviest: BH 14 MB, ggplot2 6.0 MB, data.table 5.7 MB.

Depends (1)

R >= 3.5.0

Imports (4)

rxode2statsmvtnorm data.table

LinkingTo (0)

none

Suggests (6)

lotri rmarkdown testthat ggplot2 magrittr tidyr

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Suggested by 1

Suggests, most downloaded first

nlmixr2

How these are counted

Code & Tests

People & History

People (5)

Cyril Leven

Emmanuelle Comets

Contributor

Matthew Fidler

Contributor · added in 1.2.6

Audrey Lavenu

Contributor

Marc Lavielle

Contributor

Listed in earlier versions (1)

Matthew nfidler

no longer listed · 1.2.4

Releases (6)

Pick two releases to compare their code metrics.

R
R 4.6.0 released · 2026-04-24
R
R 4.5.0 released · 2025-04-11
1.2.8Latest
record
2025-02-04 · current release · diff ↗
1.2.7
record
2024-09-13 · diff ↗ ·
added 1 export
poso_replace_et
1.2.6
record
2024-08-27 · diff ↗ ·
removed 3 exports
error_model_comb1, error_model_comb2, error_model_mixednm
R
R 4.4.0 released · 2024-04-24
1.2.4
record
2024-02-09 · diff ↗ ·
added 1 export
posologyr_error_lines
1.2.2
record
2023-06-12 · diff ↗
1.2.1
record
2023-06-05
R
R 4.3.0 released · 2023-04-21

Package metadata

First published: 2023-06-05
Total releases: 6 / 3 yrs
License: AGPL-3 OSI
Minimum R: ≥ 3.5.0
Download size: 110 KB

Appears in task views

Analysis of Pharmacokinetic Data

Cite

Cite this package

Run in R for the authors' entry:

citation("posologyr")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.3390/pharmaceutics14020442.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for posologyr version 1.2.8 [Data set]. HJJB, LLC. Data release v2026-10-19. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-19, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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