Joint Covariance and Treatment-Effect Tests for Multiple Outcomes
Overview
Fits generalized linear models, Cox proportional-hazards models, log-rank tests, generalized estimating equations, mixed models with repeated measures, Kaplan-Meier curves, quantile differences, and hierarchical net-benefit (win-difference) and log win-ratio statistics jointly across multiple endpoints, and returns the full asymptotic covariance matrix linking them. Implements PATED (Prognostic Assisted Treatment Effect Detection), a randomized-trial method that exploits balanced prognostic covariates to tighten standard errors and increase statistical power without introducing bias.
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
- ERROR12 OK, 1 ERROR2026-06-08
- OK14 OK2026-03-10
Documentation
- Help pages
- 22
- Examples that run
- 86%6 run in a plain check · 1 hold no code
- Exported functions with examples
- 15%
- Documented parameters
- 100%
- Return-value docs
- 38%
- Help pages citing references
- 18%
Downloads
Repository
7 development-tooling and community-health practices detected across 4 families in the upstream repository
Checks run against github.com/zhangh12/multipleoutcomes on 2026-10-11.
GitHub Pages site last deployed 2026-06-13 · The repository has a site deploy workflow
pkgdown site last built 2026-06-13, before release 0.18.1 (2026-06-15)
Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- 0.18.1Latest2026-06-15 · current release · diff ↗ ·
added 5 exports
nb_binary, nb_continuous, nb_tte, netbenefit_, winratio_ - 0.16.22026-05-18 · diff ↗ ·
removed 1 export
multipleOutcomesadded 9 exports
coxph_, gee_, glm_, jointCovariance, km_, logrank_, mmrm_, quantile_, simulateMoData - RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- 0.4
- RR 4.4.0 released · 2024-04-24
- 0.22024-03-08
- RR 4.3.0 released · 2023-04-21
Package metadata
- First published
- 2024-03-08
- Total releases
- 4 / 2 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 3.5
- Bundled data
- 45 KB / 4 files
- Download size
- 207 KB
Cite
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