R Observatory: Metrics for monolix2rx version 0.0.6

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

monolix2rx

0.0.6Package record

Converts 'Monolix' Models to 'rxode2'

1packages dependsuggested by 1

5.1Kdownloads / year

89.5%test coverage

13/13flavors OK

Overview

About

Maintained by Matthew FidlerCRAN page ↗GitHub ↗Website ↗

'Monolix' is a tool for running mixed effects model using 'saem'. This tool allows you to convert 'Monolix' models to 'rxode2' (Wang, Hallow and James (2016) doi:10.1002/psp4.12052) using the form compatible with 'nlmixr2' (Fidler et al (2019) doi:10.1002/psp4.12445). If available, the 'rxode2' model will read in the 'Monolix' data and compare the simulation for the population model individual model and residual model to immediately show how well the translation is performing. This saves the model development time for people who are creating an 'rxode2' model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a 'rxode2' model. This is complementary to the 'babelmixr2' package that translates 'nlmixr2' models to 'Monolix' and can convert the objects converted from 'monolix2rx' to a full 'nlmixr2' fit. While not required, you can get/install the 'lixoftConnectors' package in the 'Monolix' installation, as described at the following url https://monolixsuite.slp-software.com/r-functions/2024R1/installation-and-initialization. When 'lixoftConnectors' is available, 'Monolix' can be used to load its model library instead manually setting up text files (which only works with old versions of 'Monolix').

Changes in 0.0.6

Updated to add types for rstudio completion

From NEWS.md in the release

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("monolix2rx", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("nlmixr2/monolix2rx")

Development version from nlmixr2/monolix2rx. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-monolix2rx

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled. We list this channel from recorded r2u download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-monolix2rx

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-monolix2rx

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed). We list this channel from recorded autoCRAN download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

Health

CRAN checks

13OK

CRAN check page ↗

Slowest check: 6.2 min · r-oldrel-windows-x86_64

Status changes

OK13 OK2026-10-03
ERROR12 OK, 1 ERROR2026-09-15
OK13 OK2026-08-12
ERROR10 OK, 1 NOTE, 2 ERROR2026-08-04
NOTE12 OK, 1 NOTE2026-08-01

Show 6 earlier changesHide 6 earlier changes

OK13 OK2026-06-09
ERROR12 OK, 1 ERROR2026-06-08
OK12 OK2026-04-25
NOTE12 OK, 2 NOTE2026-04-22
ERROR11 OK, 2 NOTE, 1 ERROR2026-04-18
NOTE12 OK, 2 NOTE2026-03-10

Advisories

none known

How this is measured·How advisories are found

Documentation

In release 0.0.6

READMEYes · 521 wordsVignettesNoNEWSYes · 100% structured · mentions 0.0.6Citation fileNoWebsiteYes · pkgdown

The repository also keeps web-only articles.

Help pages: 8 (5 internal)
Examples that run: 100%3 run in a plain check
Exported functions with examples: 43%
Documented parameters: 100%
Return-value docs: 86%
Help pages citing references: 0%

How these are measured

Downloads

5.1K

CRAN downloads in the past year

Rank #5,947 · ~14/day · ~424/mo

Releases R versions

Daily download trend is not available in this view yet.

50830 days

1.4K90 days

5.1K1 year

Compare downloads with other packages →

Also on421 r2u7 autocran

How downloads are counted

Repository

nlmixr2/monolix2rx ↗Organization: nlmixr2

2Stars

0Forks

3Open issues

0Open PRs

5Releases

548Commits

2Commit identities

monolixnlmixr2pharmacometricsrxode2

548 commits · Last activity 2026-10-23 · 0% stars, 30d · Default branch at 0.0.7, ahead of CRAN 0.0.6 (checked 2026-10-21)

Responsiveness

How these are sampled

PRs merged (all time): 97%
Median days to close, 50 most recently updated closed issues: 11
Median days to close, 50 most recently updated closed PRs: 0

Stars over time

2024-12-16 · 12026-08-30 · 2

How these are measured

PracticesBeta

10 development-tooling and community-health practices detected across 5 families in the upstream repository

Checks run against github.com/nlmixr2/monolix2rx on 2026-10-21.

Continuous integration (2)

GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (4)

README.Rmdpkgdown

GitHub Pages site last deployed 2026-10-13 · The repository has a site deploy workflow

Coverage (1)

Coverage reporting

CRAN release process (2)

cran-comments.mdCRAN-SUBMISSION

Show all practicesHide 1 practice

Lint, format, editor (1)

lintr

How this is detected·Detection ruleset v4 (2026-10-20)

AI coding toolsBeta

This repository shows signs of AI coding tools.

Claude Codefirst seen 2026-04-02
Seen in the repository: CLAUDE.md
Named in .Rbuildignore: .claude, CLAUDE.md
Named in .gitignore: .claude
Pull request it wrote: opened by a project member
Commits: at least 33 crediting it in the message
GitHub Copilotfirst seen 2026-08-12
Commits: at least 2 crediting it in the message

From outside contributors

Claude Code
Pull requests: 1 from outside contributors, first on 2026-06-15

Models named in its commits

Claude Opus 5.59 commits · Sep 2026
Claude Opus 58 commits · Jul 2026
Claude Opus 4.77 commits · May 2026
Claude Fable 54 commits · Jul 2026
Claude Opus 4.84 commits · Jun 2026

1 more model not listed.

Counts are commits, not lines of code. Commits by a tool's accounts count once across all of its accounts. Commits crediting it are the largest count among its credit lines, a minimum.How this is detected·Detection ruleset v4 (updated 2026-09-27)

Dependencies

Declared dependencies

19 external dependencies (excludes base and recommended)

Installing monolix2rx adds 56 packages (38 with compiled code, 67 MB of source tarballs). Heaviest: BH 14 MB, stringi 11 MB, ggplot2 6.0 MB.

Depends (0)

none

Imports (12)

Rcpp checkmate cli dparser withr ggplot2 ggforce stringi crayon lotri magrittr rxode2

LinkingTo (3)

dparser rxode2 Rcpp

Suggests (4)

devtools testthat xgxr vdiffr

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

1direct

0indirect

Imports 1

Suggested by 1

Depends, Imports or LinkingTo, most downloaded first

babelmixr2

Suggests, most downloaded first

nlmixr2

How these are counted

Code & Tests

People & History

People (2)

Matthew Fidler

Author, Maintainer since 0.0.1 (2024)

Justin Wilkins

Contributor

Releases (6)

Pick two releases to compare their code metrics.

R
R 4.6.0 released · 2026-04-24
0.0.6Latest
record
2025-08-29 · current release · diff ↗
0.0.5
record
2025-07-15 · diff ↗
R
R 4.5.0 released · 2025-04-11
0.0.4
record
2024-11-29 · diff ↗
0.0.3
record
2024-10-24 · diff ↗
0.0.2
record
2024-09-20 · diff ↗
0.0.1
record
2024-09-20
R
R 4.4.0 released · 2024-04-24

Package metadata

First published: 2024-09-20
Total releases: 6 / 2 yrs
License: MIT + file LICENSE OSI
Download size: 801 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("monolix2rx")

Format

Fidler, M., & Wilkins, J. (2025). monolix2rx: Converts 'Monolix' Models to 'rxode2' (Version 0.0.6) [Computer software]. https://doi.org/10.32614/CRAN.package.monolix2rx

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for monolix2rx version 0.0.6 [Data set]. HJJB, LLC. Data release v2026-10-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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