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joineRML

0.4.8Package record

Joint Modelling of Multivariate Longitudinal Data and Time-to-Event Outcomes

2packages dependsuggested by 2
105.4Kdownloads / year
95.4%test coverage
13/13flavors OK

Overview

About
Maintained by Graeme L. HickeyCRAN page ↗GitHub ↗Website ↗Issues ↗Declared funder: Medical Research Council

Fits the joint model proposed by Henderson and colleagues (2000) doi:10.1093/biostatistics/1.4.465, but extended to the case of multiple continuous longitudinal measures. The time-to-event data is modelled using a Cox proportional hazards regression model with time-varying covariates. The multiple longitudinal outcomes are modelled using a multivariate version of the Laird and Ware linear mixed model. The association is captured by a multivariate latent Gaussian process. The model is estimated using a Monte Carlo Expectation Maximization algorithm. This project was funded by the Medical Research Council (Grant number MR/M013227/1).

Changes in 0.4.8

Bug fixes

  • bootSE() parallel branch condition was ncores >= 1L (always TRUE), making the serial code path with the progress bar unreachable. Corrected to ncores > 1L.
  • mjoint() now correctly throttles the number of threads used by RcppArmadillo during the MCEM algorithm via armadillo_throttle_cores() (restored on exit).
  • simData() now uses drop = FALSE when subsetting the random effects matrices in the Gompertz (model = "intslope") survival-time calculation, preventing a latent dimension-dropping error when only a single subject remains in the branch.
  • Internal initial-value calculation for the survival sub-model (initsSurv()) no longer relies on a leaked loop variable when indexing timeVar; it now uses the (outcome-invariant) first time variable explicitly in the balanced-data case.

Minor improvements

  • plot.ranef.mjoint() now uses geom_errorbar(orientation = "y") instead of the deprecated geom_errorbarh(), eliminating ggplot2 4.0 deprecation warnings.
  • simData() now reports the simulated event rate via message() rather than cat(), so output can be suppressed with suppressMessages().
  • vcov.mjoint() now warns when it falls back to the Moore-Penrose pseudo-inverse, as the approximate standard errors may be unreliable in that case.
  • Fixed documentation typos: "left hand-hand side" in mjoint(), "comprised on" in the package description, and "The choice os" in dynSurv() and dynLong().

Dependency changes

  • Minimum R version raised to 4.1.0.

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 9.5 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK12 OK2026-04-25
  • NOTE12 OK, 2 NOTE2026-04-22
  • ERROR11 OK, 2 NOTE, 1 ERROR2026-04-18
Show 1 earlier changeHide 1 earlier change
  • NOTE12 OK, 2 NOTE2026-03-10
Advisories

none known

Documentation

In release 0.4.8
READMEYes · 700 wordsVignettesYes · 3 · dynamicNEWSYes · 100% structured · mentions 0.4.8Citation fileYes · cites a publicationWebsiteYes · pkgdown
Help pages
32 (2 internal)includes a package overview page
Examples that run
5%1 run in a plain check · 18 never run
Exported functions with examples
78%
Documented parameters
98%
Return-value docs
78%
Help pages citing references
81%

Downloads

105.4K
CRAN downloads in the past year
Rank #1,351 · ~289/day · ~8.8K/mo
Daily download trend is not available in this view yet.
5.9K30 days
20.9K90 days
105.4K1 year
Compare downloads with other packages →
Also on483 r2u7 autocran195 c2d4u

Repository

34Stars
13Forks
7Open issues
0Open PRs
12Releases
470Commits
6Commit identities
longitudinal-dataregression-modelsmultivariate-longitudinal-datacoxr-packagesurvivaljoint-modelsrcpp
License file reads as GPL-3.0 · 470 commits · Last activity 2026-06-13 · 0% stars, 30d
Responsiveness
How these are sampled
PRs merged (all time)
88%
Median days to close, 50 most recently updated closed issues
22
Median days to close, 50 most recently updated closed PRs
28

Stars over time

2025-10-09 · 322026-07-07 · 34
PracticesBeta

12 development-tooling and community-health practices detected across 6 families in the upstream repository

Checks run against github.com/graemeleehickey/joinerml on 2026-10-11.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (4)
README.Rmdpkgdown

GitHub Pages site last deployed 2026-06-14 · The repository has a site deploy workflow

pkgdown site last built 2026-06-14

Coverage (1)
Coverage reporting (Codecov)
Reproducibility and dev environment (1)
data-raw/
Show all practicesHide 2 practices
CRAN release process (3)
cran-comments.mdrevdep/CRAN-SUBMISSION
Lint, format, editor (1)
RStudio project
How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies
20 external dependencies (excludes base and recommended)

Installing joineRML adds 42 packages (23 with compiled code, 32 MB of source tarballs). Heaviest: ggplot2 6.0 MB, lme4 4.1 MB, nloptr 2.1 MB.

Depends (3)
R >= 4.1.0nlmesurvival
LinkingTo (2)
Enhances (0)
none
Reverse dependencies
2direct
0indirect
Imports 2
Suggested by 2
Depends, Imports or LinkingTo, most downloaded first
Suggests, most downloaded first

Datasets

People & History

People (8)
Maintainer since 0.4.3 (2020), Author
Author · added in 0.4.0
Contributor
Contributor, Data contributor · added in 0.2.0
data/renal.rda, R/hessian.R, R/vcov.R
Contributor
Funder · added in 0.4.1
Grant number: MR/M013227/1

Previously maintained by Pete Philipson (0.4.2) and Graeme L. Hickey (0.1.0 to 0.4.1).

Releases (15)

Pick two releases to compare their code metrics.

  • 0.4.8Latest
    record
    2026-06-14 · current release · diff ↗
  • R
    R 4.6.0 released · 2026-04-24
  • R
    R 4.5.0 released · 2025-04-11
  • 0.4.7
    record
    2025-02-04 · diff ↗
  • R
    R 4.4.0 released · 2024-04-24
  • R
    R 4.3.0 released · 2023-04-21
  • 0.4.6
    record
    2023-01-20 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • 0.4.5
    record
    2021-01-05 · diff ↗
  • R
    R 4.0.0 released · 2020-04-24
  • 0.4.4
    record
    2020-04-09 · diff ↗ ·
    added 3 exports
    augment, glance, tidy
  • unarchivedReturned to CRAN
    2020-02-17
  • 0.4.3
    record
    2020-02-17 · diff ↗
  • archivedRemoved from CRAN
    2020-01-10
    check problems were not corrected in time
  • R
    R 3.6.0 released · 2019-04-26
Show 12 earlier eventsHide 12 earlier events

Package metadata

First published
2016-12-27
Total releases
15 / 10 yrs
License
GPL-3 | file LICENSE OSI
Minimum R
≥ 4.1.0
Bundled data
958 KB / 4 files
Download size
1.6 MB
Appears in task views

Cite

Cite this package

Run in R for the authors' entry:

citation("joineRML")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.1186/s12874-018-0502-1.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for joineRML version 0.4.8 [Data set]. HJJB, LLC. Data release v2026-10-19. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-19, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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