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frequentistSSDBinary

Screened Selection Design with Binary Endpoints

v0.1.0 · Jun 26, 2024 · GPL-2

Description

A study based on the screened selection design (SSD) is an exploratory phase II randomized trial with two or more arms but without concurrent control. The primary aim of the SSD trial is to pick a desirable treatment arm (e.g., in terms of the response rate) to recommend to the subsequent randomized phase IIb (with the concurrent control) or phase III. The proposed designs can “partially” control or provide the empirical type I error/false positive rate by an optimal algorithm (implemented by the optimal_2arm_binary() or optimal_3arm_binary() function) for each arm. All the design needed components (sample size, operating characteristics) are supported.

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OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Dependency Network

Dependencies Reverse dependencies mvtnorm clinfun ph2mult frequentistSSDBinary

Version History

1 tracked
new 0.1.0 Mar 10, 2026

R Observatory began tracking this package on Mar 10, 2026; it first appeared on CRAN Jun 26, 2024. Releases before tracking aren’t shown.