ePCR
0.11.0Ensemble Penalized Cox Regression for Survival Prediction
Overview
The top-performing ensemble-based Penalized Cox Regression (ePCR) framework developed during the DREAM 9.5 mCRPC Prostate Cancer Challenge https://www.synapse.org/ProstateCancerChallenge presented in Guinney J, Wang T, Laajala TD, et al. (2017) doi:10.1016/S1470-2045(16)30560-5 is provided here-in, together with the corresponding follow-up work. While initially aimed at modeling the most advanced stage of prostate cancer, metastatic Castration-Resistant Prostate Cancer (mCRPC), the modeling framework has subsequently been extended to cover also the non-metastatic form of advanced prostate cancer (CRPC). Readily fitted ensemble-based model S4-objects are provided, and a simulated example dataset based on a real-life cohort is provided from the Turku University Hospital, to illustrate the use of the package. Functionality of the ePCR methodology relies on constructing ensembles of strata in patient cohorts and averaging over them, with each ensemble member consisting of a highly optimized penalized/regularized Cox regression model. Various cross-validation and other modeling schema are provided for constructing novel model objects.
Install
Health
- NOTE r-devel-linux-x86_64-debian-clang
- NOTE r-devel-linux-x86_64-debian-gcc
- NOTE2026-06-0911 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- ERROR2026-06-0811 OK · 1 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
- NOTE2026-03-1012 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Documentation
- Examples that run
- 93%
- Documented parameters
- 92%
- Return-value docs
- 82%
- References docs
- 20%
Downloads
Dependencies
Code & Tests
Datasets
People & History
Author records are not tracked yet for this package.
5 releases. Pick two to compare their code metrics. R releases are shown for context.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- 0.11.0Latest
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- RR 4.0.0 released · 2020-04-24
- 0.9.9-112019-11-24 · diff ↗
- RR 3.6.0 released · 2019-04-26
- 0.9.9-92019-04-11 · diff ↗
- 0.9.9-62018-05-29 · diff ↗
- RR 3.5.0 released · 2018-04-23
- 0.9.9-42017-12-21
- RR 3.4.0 released · 2017-04-21
Package metadata
- First published
- 2017-12-21
- Total releases
- 5 / 9 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 3.5.0
- Bundled data
- 4.0 MB / 2 files
- Download size
- 4.1 MB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet
Cite
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