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driveR

0.5.0Package record

Prioritizing Cancer Driver Genes Using Genomics Data

0packages depend
3.5Kdownloads / year
–test coverage
13/13flavors OK

Overview

About

Cancer genomes contain large numbers of somatic alterations but few genes drive tumor development. Identifying cancer driver genes is critical for precision oncology. Most of current approaches either identify driver genes based on mutational recurrence or using estimated scores predicting the functional consequences of mutations. 'driveR' is a tool for personalized or batch analysis of genomic data for driver gene prioritization by combining genomic information and prior biological knowledge. As features, 'driveR' uses coding impact metaprediction scores, non-coding impact scores, somatic copy number alteration scores, hotspot gene/double-hit gene condition, 'phenolyzer' gene scores and memberships to cancer-related KEGG pathways. It uses these features to estimate cancer-type-specific probability for each gene of being a cancer driver using the related task of a multi-task learning classification model. The method is described in detail in Ulgen E, Sezerman OU. 2021. driveR: driveR: a novel method for prioritizing cancer driver genes using somatic genomics data. BMC Bioinformatics doi:10.1186/s12859-021-04203-7.

Changes in 0.5.0

Major Changes

  • added support for gene-level SCNA data frames to be used as input for create_features_df() and added an example gene-level SCNA data frame example_gene_scna_table

Minor changes and bug fixes

  • Moved org.Hs.eg.db, TxDb.Hsapiens.UCSC.hg19.knownGene and TxDb.Hsapiens.UCSC.hg38.knownGene from "Imports" to "Suggests" per new CRAN policy. Relevant functions raise error if the required package is not installed.

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 3.9 min · r-oldrel-macos-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-06-27
  • ERROR12 OK, 1 ERROR2026-06-21
  • OK13 OK2026-06-09
Show 8 earlier changesHide 8 earlier changes
  • ERROR12 OK, 1 ERROR2026-06-08
  • OK13 OK2026-05-10
  • ERROR12 OK, 1 ERROR2026-05-03
  • OK13 OK2026-05-02
  • ERROR11 OK, 1 ERROR2026-04-25
  • NOTE11 OK, 3 NOTE2026-04-16
  • ERROR10 OK, 3 NOTE, 1 ERROR2026-04-09
  • NOTE11 OK, 3 NOTE2026-03-10
Advisories

none known

Documentation

In release 0.5.0
READMEYes · 295 wordsVignettesYes · 1 · dynamicNEWSYes · 100% structured · mentions 0.5.0Citation fileYes · cites a publicationWebsiteYes · pkgdown
Help pages
17includes a package overview page
Examples that run
100%2 run in a plain check
Exported functions with examples
67%
Documented parameters
100%
Return-value docs
100%
Help pages citing references
0%
Vignettes (1)

Downloads

3.5K
CRAN downloads in the past year
Rank #9,053 · ~10/day · ~290/mo
Daily download trend is not available in this view yet.
40430 days
1.1K90 days
3.5K1 year
Compare downloads with other packages →
Also on1.6K r2u

Repository

17Stars
1Forks
0Open issues
0Open PRs
7Releases
215Commits
1Commit identities
cancer-drivernessidentify-driver-genesscoringranking-genesdriver-gene-prioritizationdriver
215 commits · Last activity 2025-12-22 · Default branch at 0.5.0.9000, ahead of CRAN 0.5.0 (checked 2026-10-22)
Responsiveness
How these are sampled
PRs merged (all time)
100%
Median days to close, 50 most recently updated closed issues
0
Median days to close, 50 most recently updated closed PRs
0

Stars over time

2025-05-07 · 172026-07-07 · 17
PracticesBeta

9 development-tooling and community-health practices detected across 5 families in the upstream repository

Checks run against github.com/egeulgen/driver on 2026-10-22.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (4)
README.Rmdpkgdown

GitHub Pages site last deployed 2025-12-22 · The repository has a site deploy workflow

pkgdown site last built 2025-12-22

Coverage (1)
Coverage reporting (Codecov)
CRAN release process (1)
cran-comments.md
Show all practicesHide 1 practice
Lint, format, editor (1)
RStudio project
How this is detected·Detection ruleset v4 (2026-10-20)

Dependencies

Declared dependencies
14 external dependencies (excludes base and recommended)

Installing driveR adds 64 packages (35 with compiled code, 48 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, data.table 5.7 MB. 4 more not on CRAN are not measured.

Depends (1)
R >= 4.0
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (1)
Author, Maintainer since 0.1.1 (2020), Copyright holder
Releases (7)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • 0.5.0Latest
    record
    2025-12-22 · current release · diff ↗
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • 0.4.1
    record
    2023-08-19 · diff ↗
  • R
    R 4.3.0 released · 2023-04-21
  • 0.4.0
    record
    2022-08-15 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • 0.3.0
    record
    2022-01-18 · diff ↗
  • R
    R 4.1.0 released · 2021-05-18
  • 0.2.1
    record
    2020-11-26 · diff ↗
  • 0.2.0
    record
    2020-11-19 · diff ↗
  • 0.1.1
    record
    2020-11-18
  • R
    R 4.0.0 released · 2020-04-24

Package metadata

First published
2020-11-18
Total releases
7 / 6 yrs
License
MIT + file LICENSE OSI
Minimum R
≥ 4.0
Bundled data
1.5 MB / 8 files
Download size
2.6 MB

Cite

Cite this package

Run in R for the authors' entry:

citation("driveR")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.1186/s12859-021-04203-7.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for driveR version 0.5.0 [Data set]. HJJB, LLC. Data release v2026-10-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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