Guide Sequence Design for CRISPR/Cas9
Overview
Designs guide sequences for CRISPR/Cas9 genome editing and provides information on sequence features pertinent to guide efficiency. Sequence features include annotated off-target predictions in a user-selected genome and a predicted efficiency score based on the model described in Doench et al. (2016) doi:10.1038/nbt.3437. Users are able to import additional genomes and genome annotation files to use when searching and annotating off-target hits. All guide sequences and off-target data can be generated through the 'R' console with sgRNA_Design() or through 'crispRdesignR's' user interface with crispRdesignRUI(). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and the associated protein Cas9 refer to a technique used in genome editing.
Install
Health
NOTEdependencies in R coder-devel-linux-x86_64-fedora-clang, r-devel-linux-x86_64-fedora-gcc
Namespace in Imports field not imported from: ‘DT’ All declared Imports should be used.
- NOTE11 OK, 2 NOTE2026-06-09
- ERROR10 OK, 2 NOTE, 1 ERROR2026-06-08
- NOTE11 OK, 2 NOTE2026-05-10
- ERROR10 OK, 2 NOTE, 1 ERROR2026-05-03
- NOTE10 OK, 4 NOTE2026-03-10
Documentation
- Help pages
- 6
- Examples that run
- 100%4 run in a plain check
- Exported functions with examples
- 67%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 0%
Downloads
Repository
- PRs merged (all time)
- not measured
- Median days to close, 50 most recently updated closed issues
- 17
- Median days to close, 50 most recently updated closed PRs
- not measured
Stars over time
Forks over time
Issues over time
Checks run against github.com/dylanbeeber/crisprdesignr on 2026-10-11.
No development-tooling practices detected in the upstream repository.
Dependencies
Installing crispRdesignR adds 47 packages (25 with compiled code, 46 MB of source tarballs). Heaviest: stringi 11 MB, bslib 5.6 MB, promises 3.1 MB. 7 more not on CRAN are not measured.
Code & Tests
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- unarchivedReturned to CRAN2023-04-12
- 1.1.7Latest
- archivedRemoved from CRAN2022-12-19issues were not corrected in time
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- 1.1.62021-01-11 · diff ↗
- 1.1.52020-05-26
- RR 4.0.0 released · 2020-04-24
Package metadata
- First published
- 2020-05-26
- Total releases
- 3 / 6 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 2.10
- Download size
- 1.2 MB
Cite
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citation("crispRdesignR")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
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