Skip to content

coFAST

Spatially-Aware Cell Clustering Algorithm with Cluster Significant Assessment

v0.2.0 · Dec 13, 2025 · GPL-3

Description

A spatially-aware cell clustering algorithm is provided with cluster significance assessment. It comprises four key modules: spatially-aware cell-gene co-embedding, cell clustering, signature gene identification, and cluster significant assessment. More details can be referred to Peng Xie, et al. (2025) <doi:10.1016/j.cell.2025.05.035>.

Downloads

204

Last 30 days

22149th

480

Last 90 days

863

Last year

Trend: +28.3% (30d vs prior 30d)

CRAN Check Status

2 ERROR
12 OK
Show all 14 flavors
Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 ERROR
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 ERROR
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (3 non-OK)
NOTE r-oldrel-macos-arm64

package dependencies

Package suggested but not available for checking: ‘scater’
ERROR r-oldrel-macos-arm64

whether package can be installed

Installation failed.
See ‘/Volumes/Builds/packages/big-sur-arm64/results/4.4/coFAST.Rcheck/00install.out’ for details.
ERROR r-release-macos-arm64

examples

Running examples in ‘coFAST-Ex.R’ failed
The error most likely occurred in:

> ### Name: diagnostic.cor.eigs
> ### Title: Determine the dimension of low dimensional embedding
> ### Aliases: diagnostic.cor.eigs diagnostic.cor.eigs.default
> ###   diagnostic.cor.eigs.Seurat
> 
> ### ** Examples
> 
> n <- 100
> p <- 50
> d <- 15
> object <- matrix(rnorm(n*d), n, d) %*% matrix(rnorm(d*p), d, p)
> diagnostic.cor.eigs(object, n.sims=2)
Warning in diagnostic.cor.eigs.default(object, n.sims = 2) :
  q_max is not less than the number of columns of X. Set it as ncol(X) - 1
Warning in irlba::irlba(A = Y/sqrt(n), nv = q_max) :
  You're computing too large a percentage of total singular values, use a standard svd instead.

 Progress: ──────────────────────────────────────────────────────────────── 100%
 *** caught segfault ***
address 0x110, cause 'invalid permissions'

 *** caught segfault ***
address 0x110, cause 'invalid permissions'

Traceback:
 1: irlba::irlba(A = X1/sqrt(n), nv = q_max)
 2: .
...[truncated]...
 = "map",     env_globals = .env_globals)
60: furrr::future_map(1:n.sims, corr_fun, n = n, p = p, .progress = TRUE,     .options = furrr::furrr_options(seed = seed))
61:     progress = .progress, type = "list", purrr_fn_name = "map",     env_globals = .env_globals)
60: furrr::future_map(1:n.sims, corr_fun, n = n, p = p, .progress = TRUE,     .options = furrr::furrr_options(seed = seed))
61: diagnostic.cor.eigs.default(object, n.sims = 2)diagnostic.cor.eigs.default(object, n.sims = 2)
62: diagnostic.cor.eigs(object, n.sims = 2)

62: diagnostic.cor.eigs(object, n.sims = 2)
An irrecoverable exception occurred. R is aborting now ...
An irrecoverable exception occurred. R is aborting now ...
Warning in file(file, open = "r") :
  cannot open file '/Volumes/Temp/tmp/RtmpVtOrBv/filee7b57d9208b0.txt': No such file or directory
Error in file(file, open = "r") : cannot open the connection
Calls: diagnostic.cor.eigs ... furrr_map_template -> furrr_template -> poll_progress -> file
Execution halted

Check History

ERROR 11 OK · 0 NOTE · 0 WARNING · 3 ERROR · 0 FAILURE Mar 10, 2026
ERROR r-devel-macos-arm64

package dependencies

Package required but not available: ‘ProFAST’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-arm64

examples

Running examples in ‘coFAST-Ex.R’ failed
The error most likely occurred in:

> ### Name: diagnostic.cor.eigs
> ### Title: Determine the dimension of low dimensional embedding
> ### Aliases: diagnostic.cor.eigs diagnostic.cor.eigs.default
> ###   diag
...[truncated]...
2>) of class MulticoreFuture was interrupted, while running on localhost (pid 73002) [future <unnamed-2> (30561e877663b5105e3b175a2a88ecee-2); on 30561e877663b5105e3b175a2a88ecee@macos13-vm.local<72998> at 2026-03-11 03:44:51.021652]
Execution halted
ERROR r-oldrel-macos-arm64

package dependencies

Package suggested but not available for checking: ‘scater’

Dependency Network

Dependencies Reverse dependencies Rcpp furrr future ggplot2 irlba DR.SC PRECAST ProFAST Matrix ade4 progress pbapply dplyr Seurat coFAST

Version History

new 0.2.0 Mar 10, 2026
updated 0.2.0 ← 0.1.0 diff Dec 13, 2025
new 0.1.0 Nov 16, 2025