An R Implementation of the 'Align-GVGD' Method
Overview
'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments doi:10.1136/jmg.2005.033878. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on http://agvgd.hci.utah.edu/.
- Fixed a bug with
read_substitutions()that would not parse positions correctly. - Added a new substitutions example file
lee2010_sub.txt. - Added a new function
read_agvgdweb_results()aimed at developers.
From NEWS.md in the release
Install
Health
- OK13 OK2026-09-08
- ERROR12 OK, 1 ERROR2026-09-07
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
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- ERROR12 OK, 1 ERROR2026-06-08
- OK14 OK2026-03-10
Documentation
- Help pages
- 18 (4 internal)includes a package overview page
- Examples that run
- 100%13 run in a plain check
- Exported functions with examples
- 81%
- Documented parameters
- 94%
- Return-value docs
- 100%
- Help pages citing references
- 6%
Downloads
Repository
- PRs merged (all time)
- not measured
- Median days to close, 50 most recently updated closed issues
- 1
- Median days to close, 50 most recently updated closed PRs
- not measured
Stars over time
Forks over time
Issues over time
10 development-tooling and community-health practices detected across 6 families in the upstream repository
Checks run against github.com/maialab/agvgd on 2026-10-25.
The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel
GitHub Pages site last deployed 2023-12-16 · The repository has a site deploy workflow
pkgdown site last built 2023-12-16
Show all practicesHide 2 practices
Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- 0.1.2Latest2022-09-10 · current release · diff ↗ ·
added 4 exports
profile_to_alignment, read_agvgdweb_results, write_alignment, write_substitutions - RR 4.2.0 released · 2022-04-22
- 0.1.12022-02-03 · diff ↗ ·
removed 3 exports
align_gvgd, alignment_pos_to_residue_pos, residue_pos_to_alignment_posadded 6 exports
cpv_ranges, dev, gd, gv, poi_to_res, res_to_poi - 0.1.02022-01-17
- RR 4.1.0 released · 2021-05-18
Package metadata
- First published
- 2022-01-17
- Total releases
- 3 / 4 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 2.10
- Download size
- 1.3 MB
Cite
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