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ViralEntropR

0.6.2Package record

A Computational Pipeline for Entropy-Informed Detection of Emerging Viral Variants

0packages depend
1.4Kdownloads / year
–test coverage
13/13flavors OK

Overview

About

Implements an entropy-informed pipeline for detecting emerging variants in viral amino acid sequence data, extending prior clustering-based approaches including hemagglutinin clustering methods (Li et al., 2015) doi:10.1142/9789814667944_0018. Provides a fully vectorized FASTA preprocessing toolkit covering header parsing, two-pass date and country extraction, ambiguous-residue filtering, and integer encoding under a 25-symbol amino acid alphabet. Computes per-site Shannon entropy across user-defined cumulative, sliding, or disjoint temporal partitions and clusters per-site entropy values using Gaussian mixture models via 'mclust' (Scrucca et al., 2016) doi:10.32614/RJ-2016-021. Quantifies temporal distributional shifts between partitions using the Hellinger distance (van der Vaart, 1998) doi:10.1017/CBO9780511802256, and detects temporal change points non-parametrically using energy statistics (Matteson and James, 2014) doi:10.1080/01621459.2013.849605 via 'ecp' or wild binary segmentation (Fryzlewicz, 2014) doi:10.1214/14-AOS1245 via 'HDcpDetect'. Per-site amino-acid frequency tables and entropy trajectory plots characterize sequence composition and evolutionary dynamics across time. A configurable multi-variant simulation engine generates synthetic sequence time series with known ground truth for benchmarking detection pipelines. A curated dataset of SARS-CoV-2 Variants of Concern and Variants of Interest with associated lineage and surveillance metadata is included, along with a bundled National Center for Biotechnology Information (NCBI) Spike protein sample and vignettes demonstrating the full workflow.

Changes in 0.6.2
  • Additional CRAN feedback addressed in resubmission:
  • The \dontrun{} block in the sarscov2_variants dataset example that calls References$display() (which requires DT, in Suggests) was missed in the prior audit. The block is now wrapped in if (interactive() && requireNamespace("DT", quietly = TRUE)), the CRAN-recommended pattern for examples that depend on Suggests packages and are intended for interactive use.

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 2.4 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK5 OK2026-05-31
Advisories

none known

Documentation

In release 0.6.2
READMEYes · 2,546 wordsVignettesYes · 3 · staticNEWSYes · 100% structured · mentions 0.6.2Citation fileNoWebsiteYes · pkgdown
Description cites an R Journal article
Help pages
23 (4 internal)includes a package overview page
Examples that run
79%15 run in a plain check · 4 only when donttest examples are enabled (R CMD check --as-cran)
Exported functions with examples
100%
Documented parameters
95%
Return-value docs
100%
Help pages citing references
4% with a bibliography file

Downloads

1.4K
CRAN downloads in the past year
Rank #16,974 · ~4/day · ~117/mo
Daily download trend is not available in this view yet.
25930 days
74190 days
1.4K1 year
Compare downloads with other packages →
Also on23 r2u3 autocran

Repository

0Stars
0Forks
0Open issues
0Open PRs
0Releases
bioinformaticschange-point-detectionclusteringcomputational-biologycovid-19fastafunctional-data-analysisgaussian-mixture-models
Last activity 2026-05-31
Responsiveness
not measured
PracticesBeta

11 development-tooling and community-health practices detected across 7 families in the upstream repository

Checks run against github.com/vadimtyuryaev/viralentropr on 2026-10-18.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (4)
README.Rmdpkgdown

GitHub Pages site last deployed 2026-05-31 · The repository has a site deploy workflow

pkgdown site last built 2026-05-31

Reproducibility and dev environment (1)
data-raw/
CRAN release process (1)
cran-comments.md
Show all practicesHide 3 practices
Research and citation (1)
CITATION.cff
Lint, format, editor (1)
RStudio project
Git structural (1)
.gitattributes
How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies
19 external dependencies (excludes base and recommended)

Installing ViralEntropR adds 55 packages (32 with compiled code, 54 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, bslib 5.6 MB.

Depends (1)
R >= 3.5.0
LinkingTo (0)
none
Enhances (0)
none
Dependencies facing archival

CRAN will archive these unless their check problems are fixed by the date shown. This package needs each one to install.

Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (3)
Author, Maintainer since 0.6.2 (2026)
Releases (1)
  • 0.6.2Latest
    2026-05-30 · current release
  • R
    R 4.6.0 released · 2026-04-24

Package metadata

First published
2026-05-30
Total releases
1 / 1 yrs
License
MIT + file LICENSE OSI
Minimum R
≥ 3.5.0
Bundled data
46 KB / 1 file
Download size
1.8 MB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("ViralEntropR")
Tyuryaev, V., Heffernan, J., & Jankowski, H. (2026). ViralEntropR: A Computational Pipeline for Entropy-Informed Detection of Emerging Viral Variants (Version 0.6.2) [Computer software]. https://doi.org/10.32614/CRAN.package.ViralEntropR

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

The repository also keeps a CITATION.cff.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for ViralEntropR version 0.6.2 [Data set]. HJJB, LLC. Data release v2026-10-20. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-20, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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