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SuperCell

Simplification of scRNA-Seq Data by Merging Together Similar Cells

v1.1 · Dec 16, 2025 · GPL-3

Description

Aggregates large single-cell data into metacell dataset by merging together gene expression of very similar cells. 'SuperCell' uses 'velocyto.R' <doi:10.1038/s41586-018-0414-6> <https://github.com/velocyto-team/velocyto.R> for RNA velocity and 'WeightedCluster' <doi:10.12682/lives.2296-1658.2013.24> <https://mephisto.unige.ch/weightedcluster/> for weighted clustering on metacells. We also recommend installing 'scater' Bioconductor package <doi:10.18129/B9.bioc.scater> <https://bioconductor.org/packages/release/bioc/html/scater.html>.

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CRAN Check Status

13 OK
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Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 9, 2026
ERROR 12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Jun 8, 2026
ERROR r-devel-linux-x86_64-debian-gcc

package dependencies

Packages required but not available: 'weights', 'Hmisc'

Packages suggested but not available for checking:
  'scater', 'Seurat', 'bluster', 'velocyto.R'

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE May 2, 2026
ERROR 11 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Apr 25, 2026
ERROR r-release-macos-x86_64

package dependencies

Package required but not available: ‘weights’

Package suggested but not available for checking: ‘velocyto.R’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Apr 10, 2026
NOTE r-oldrel-macos-arm64

package dependencies

Packages suggested but not available for checking: 'scater', 'velocyto.R'
NOTE r-oldrel-macos-x86_64

package dependencies

Package suggested but not available for checking: ‘velocyto.R’
NOTE r-oldrel-windows-x86_64

package dependencies

Package suggested but not available for checking: 'velocyto.R'
ERROR 10 OK · 3 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Apr 9, 2026
ERROR r-devel-linux-x86_64-debian-gcc

re-building of vignette outputs

Error(s) in re-building vignettes:
  ...
--- re-building ‘a_SuperCell.Rmd’ using rmarkdown

Quitting from a_SuperCell.Rmd:239-244 [Seurat]
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
<error/rlang_error>
Error in `
...[truncated]...
vs_independent_sample_processing.Rmd’ using rmarkdown
--- finished re-building ‘b_Combined_vs_independent_sample_processing.Rmd’

SUMMARY: processing the following file failed:
  ‘a_SuperCell.Rmd’

Error: Vignette re-building failed.
Execution halted
NOTE r-oldrel-macos-arm64

package dependencies

Packages suggested but not available for checking: 'scater', 'velocyto.R'
NOTE r-oldrel-macos-x86_64

package dependencies

Package suggested but not available for checking: ‘velocyto.R’
NOTE r-oldrel-windows-x86_64

package dependencies

Package suggested but not available for checking: 'velocyto.R'
NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
NOTE r-oldrel-macos-arm64

package dependencies

Packages suggested but not available for checking: 'scater', 'velocyto.R'
NOTE r-oldrel-macos-x86_64

package dependencies

Package suggested but not available for checking: ‘velocyto.R’
NOTE r-oldrel-windows-x86_64

package dependencies

Package suggested but not available for checking: 'velocyto.R'

Dependency Network

Dependencies Reverse dependencies igraph RANN corpcor weights Hmisc Matrix matrixStats plyr irlba patchwork ggplot2 umap entropy Rtsne dbscan +4 more dependencies SuperCell

Version History

4 tracked
new 1.1 Mar 10, 2026
updated 1.1 ← 1.0.1 diff Dec 15, 2025
updated 1.0.1 ← 1.0 diff Oct 24, 2024
new 1.0 Sep 4, 2024