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Rcurvep

1.3.2Package record

Concentration-Response Data Analysis using Curvep

0packages depend
6.4Kdownloads / year
82.6%test coverage
13/13flavors OK

Overview

About

An R interface for processing concentration-response datasets using Curvep, a response noise filtering algorithm. The algorithm was described in the publications (Sedykh A et al. (2011) doi:10.1289/ehp.1002476 and Sedykh A (2016) doi:10.1007/978-1-4939-6346-1_14). Other parametric fitting approaches (e.g., Hill equation) are also adopted for ease of comparison. 3-parameter Hill equation from 'tcpl' package (Filer D et al., doi:10.1093/bioinformatics/btw680) and 4-parameter Hill equation from Curve Class2 approach (Wang Y et al., doi:10.2174/1875397301004010057) are available. Also, methods for calculating the confidence interval around the activity metrics are also provided. The methods are based on the bootstrap approach to simulate the datasets (Hsieh J-H et al. doi:10.1093/toxsci/kfy258). The simulated datasets can be used to derive the baseline noise threshold in an assay endpoint. This threshold is critical in the toxicological studies to derive the point-of-departure (POD).

Changes in 1.3.2
  • change: fix a bug in the cal_fit_dataset when doing run_fit with hill bootstrap with a specific direction
  • change: add more descriptions on CARR parameter
  • change: update the vignette for the parallel computing

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 4.8 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-05-09
  • WARNING12 OK, 1 WARNING2026-05-08
  • OK14 OK2026-04-06
Show 2 earlier changesHide 2 earlier changes
  • ERROR13 OK, 1 ERROR2026-04-04
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 1.3.2
READMEYes · 179 wordsVignettesYes · 2 · dynamicNEWSYes · 67% structured · mentions 1.3.2Citation fileNoWebsiteYes · pkgdown
Help pages
20 (1 internal)includes a package overview page
Examples that run
86%12 run in a plain check · 2 only when donttest examples are enabled (R CMD check --as-cran)
Exported functions with examples
93%
Documented parameters
100%
Return-value docs
100%
Help pages citing references
10% with a bibliography file

Downloads

6.4K
CRAN downloads in the past year
Rank #8,895 · ~17/day · ~531/mo
Daily download trend is not available in this view yet.
37630 days
1.1K90 days
6.4K1 year
Compare downloads with other packages →
Also on99 r2u5 autocran

Repository

3Stars
0Forks
3Open issues
0Open PRs
8Releases
206Commits
1Commit identities
206 commits · Last activity 2025-05-30
Responsiveness
How these are sampled
PRs merged (all time)
100%
Median days to close, 50 most recently updated closed issues
1,124
Median days to close, 50 most recently updated closed PRs
0

Issues over time

2026-07-14 · 22026-07-24 · 3
PracticesBeta

8 development-tooling and community-health practices detected across 5 families in the upstream repository

Checks run against github.com/moggces/rcurvep on 2026-10-21.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (3)
pkgdown

GitHub Pages site last deployed 2025-05-28 · The repository has a site deploy workflow

pkgdown site last built 2025-06-04

Reproducibility and dev environment (1)
data-raw/
CRAN release process (1)
cran-comments.md
Show all practicesHide 1 practice
Lint, format, editor (1)
RStudio project
How this is detected·Detection ruleset v4 (2026-10-20)

Dependencies

Declared dependencies
17 external dependencies (excludes base and recommended)

Installing Rcurvep adds 38 packages (19 with compiled code, 32 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, isoband 1.5 MB.

Depends (1)
R >= 3.5
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (6)
Author, Maintainer since 1.2.0 (2021)
Author · added in 1.3.1
Contributor · added in 1.3.1
Contributor · added in 1.3.1
Contributor · added in 1.3.1
Releases (4)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • 1.3.2Latest
    record
    2025-05-31 · current release · diff ↗
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • 1.3.1
    record
    2024-01-09 · diff ↗ ·
    added 1 export
    fit_cc2_modl
  • R
    R 4.3.0 released · 2023-04-21
  • 1.2.1
    record
    2022-08-25 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • 1.2.0
    record
    2021-01-07
  • R
    R 4.0.0 released · 2020-04-24

Package metadata

First published
2021-01-07
Total releases
4 / 5 yrs
License
MIT + file LICENSE OSI
Minimum R
≥ 3.5
Bundled data
588 KB / 4 files
Download size
5.5 MB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("Rcurvep")
Hsieh, J., Huang, R., Parham, F., Sedykh, A., Wang, Y., & Zhao, T. (2025). Rcurvep: Concentration-Response Data Analysis using Curvep (Version 1.3.2) [Computer software]. https://doi.org/10.32614/CRAN.package.Rcurvep

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for Rcurvep version 1.3.2 [Data set]. HJJB, LLC. Data release v2026-10-25. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-25, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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