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ToxCast Data Analysis Pipeline

0packages dependsuggested by 3
11.1Kdownloads / year
21.1%test coverage
10/13flavors OK

Overview

About

The ToxCast Data Analysis Pipeline ('tcpl') is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, 'invitrodb'. The package was developed for the chemical screening data curated by the US EPA's Toxicity Forecaster (ToxCast) program, but 'tcpl' can be used to support diverse chemical screening efforts.

Changes in 3.3.1

Minor improvements and fixes

  • Update ctxR and API host server connection for invitrodb v4.2 access (#374)

From NEWS.md in the release

Install

Health

CRAN checks
1ERROR2NOTE10OK
Check messages
ERRORre-building of vignette outputsr-release-macos-arm64
Error(s) in re-building vignettes:
--- re-building ‘Introduction_Appendices.Rmd’ using rmarkdown
Error: processing vignette 'Introduction_Appendices.Rmd' failed with diagnostics:
pandoc document conversion failed with error 2
--- failed re-building ‘Introduction_Appendices.Rmd’

SUMMARY: processing the following file failed:
  ‘Introduction_Appendices.Rmd’

Error: Vignette re-building failed.
Execution halted

* checking PDF version of manual ...* using check arguments '--no-clean-on-error '
NOTERd contentsr-devel-linux-x86_64-debian-clang, r-devel-linux-x86_64-debian-gcc
Rd files without \usage:
  ‘mc5.Rd’
\arguments should not be documented without \usage.

CRAN check page ↗

Slowest check: 9.1 min · r-oldrel-windows-x86_64
Status changes
  • ERROR10 OK, 2 NOTE, 1 ERRORNow
  • ERROR11 OK, 1 ERROR2026-04-27
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 3.3.1
READMEYes · 244 wordsVignettesYes · 1 · dynamicNEWSYes · 100% structured · mentions 3.3.1Citation fileNoWebsiteYes
Help pages
101
Examples that run
21%6 run in a plain check · 22 never run
Exported functions with examples
68%
Documented parameters
98%
Return-value docs
53%
Help pages citing references
0%

Downloads

11.1K
CRAN downloads in the past year
Rank #5,501 · ~30/day · ~924/mo
Daily download trend is not available in this view yet.
55030 days
1.5K90 days
11.1K1 year
Compare downloads with other packages →
Also on90 r2u1.8K conda_forge

Repository

46Stars
21Forks
30Open issues
1Open PRs
4Releases
1,403Commits
29Commit identities
ordcomptoxcctetoxcastresearch
1,403 commits · Last activity 2025-10-16 · 0% stars, 30d · The default branch showed an older version (3.3.0.9000) than CRAN on 2026-10-11 · Discussions: 5 posts
Responsiveness
How these are sampled
PRs merged (all time)
93%
Median days to close, 50 most recently updated closed issues
26
Median days to close, 50 most recently updated closed PRs
2

Stars over time

2025-09-20 · 402026-08-22 · 46
PracticesBeta

7 development-tooling and community-health practices detected across 6 families in the upstream repository

Checks run against github.com/usepa/comptox-toxcast-tcpl on 2026-10-11.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Governance and community (1)
Contributing guide
Docs source (1)
README.Rmd
Coverage (1)
Coverage reporting
Show all practicesHide 2 practices
Reproducibility and dev environment (1)
data-raw/
CRAN release process (1)
cran-comments.md
How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies
31 external dependencies (excludes base and recommended)

Installing tcpl adds 97 packages (50 with compiled code, 89 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, data.table 5.7 MB.

Depends (1)
R >= 4.1.0
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect
Suggested by 3
Suggests, most downloaded first

Datasets

People & History

People (18)
Maintainer since 3.2.1 (2025) · added in 3.0.0
Contributor · added in 2.0.0
Contributor · added in 3.2.0
Contributor · added in 3.0.0
Contributor · added in 3.1.0
Contributor · added in 3.3.0
Contributor, Thesis advisor
Contributor · added in 3.3.0
Contributor · added in 3.1.0
Show 8 more contributorsHide 8 contributors
Contributor · added in 3.0.0
Contributor
Contributor, Thesis advisor
Contributor · added in 2.0.2
Contributor
Contributor · added in 3.1.0
Contributor · added in 3.3.0
Contributor · added in 2.0.2

Previously maintained by Jason Brown (3.0.0 to 3.2.0) and Richard S Judson (2.0.0 to 2.1.0).

Releases (14)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • 3.3.1Latest
    record
    2025-10-17 · current release · diff ↗
  • 3.3.0
    record
    2025-05-05 · diff ↗
  • R
    R 4.5.0 released · 2025-04-11
  • 3.2.1
    record
    2025-04-09 · diff ↗
  • 3.2.0
    record
    2024-10-09 · diff ↗ ·
    removed 2 exports
    tcplConfExample, tcplLoadClib
    added 5 exports
    tcplLoadChemList, tcplLoadConcUnit, tcplLoadUnit, tcplPlotLoadData, tcplQueryAPI
  • R
    R 4.4.0 released · 2024-04-24
  • 3.1.0
    record
    2023-10-06 · diff ↗ ·
    added 1 export
    tcplDefine
  • R
    R 4.3.0 released · 2023-04-21
  • 3.0.1
    record
    2022-11-08 · diff ↗
  • 3.0.0
    record
    2022-08-31 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • 2.1.0
    record
    2022-03-03 · diff ↗ ·
    added 1 export
    tcplPlot
  • R
    R 4.1.0 released · 2021-05-18
  • R
    R 4.0.0 released · 2020-04-24
  • 2.0.2
    record
    2019-07-26 · diff ↗
Show 9 earlier eventsHide 9 earlier events
  • R
    R 3.6.0 released · 2019-04-26
  • 2.0.1
    record
    2018-11-16 · diff ↗
  • 2.0.0
    record
    2018-11-10 · diff ↗ ·
    added 7 exports
    tcplConfExample, tcplGetAeid, tcplLvlCount, tcplMakeAeidMultiPlts, tcplMakeChidMultiPlts, tcplMultiplot, tcpldbStats
  • 1.4.3
    record
    2018-05-20 · diff ↗
  • 1.2.2
    record
    2018-05-10 · diff ↗
  • R
    R 3.5.0 released · 2018-04-23
  • R
    R 3.4.0 released · 2017-04-21
  • 1.2
    record
    2016-05-07
  • R
    R 3.3.0 released · 2016-05-03

Package metadata

First published
2016-05-07
Total releases
14 / 10 yrs
License
MIT + file LICENSE OSI · relicensed from GPL-2 in 3.0.0
Minimum R
≥ 4.1.0
Bundled data
131 KB / 10 files
Download size
2.6 MB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("tcpl")
Feshuk, M., Brown, J., Carstens, K., Davidson-Fritz, S. E., Dunham, K., Filer, D. L., Gilson, E., Judson, R. S., Knupp, L., Ko, A., Kolaczkowski, L., Kothiya, P., Martin, M. T., Paul Friedman, K., Setzer, W. R., Thunes, C., Zhao, Z., & Zurlinden, T. (2025). tcpl: ToxCast Data Analysis Pipeline (Version 3.3.1) [Computer software]. https://doi.org/10.32614/CRAN.package.tcpl

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for tcpl version 3.3.1 [Data set]. HJJB, LLC. Data release v2026-10-19. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-19, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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