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POINT

1.4

Protein Structure Guided Local Test

0packages depend
6.5Kdownloads / year
test coverage
13/13checks pass

Overview

About
Maintained by Shannon T. HollowayFirst published 2019-03-054 releasesCRAN page ↗

Provides an implementation of a rare variant association test that utilizes protein tertiary structure to increase signal and to identify likely causal variants. Performs structure-guided collapsing, which leads to local tests that borrow information from neighboring variants on a protein and that provide association information on a variant-specific level. For details of the implemented method see West, R. M., Lu, W., Rotroff, D. M., Kuenemann, M., Chang, S-M., Wagner M. J., Buse, J. B., Motsinger-Reif, A., Fourches, D., and Tzeng, J-Y. (2019) doi:10.1371/journal.pcbi.1006722.

Install

Health

CRAN checks
13OK
Slowest check: 1.5 min · r-oldrel-windows-x86_64
Code health
None
Tests · ratio 0.00
not tracked
Coverage
100%
Documentation · exports
5
Dependencies · direct
Check history
  • OK2026-08-05
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • NOTE2026-08-01
    12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • OK2026-03-10
    14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation
READMENoVignettesNopkgdown siteNoNEWSYes · 33% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
100%
Return-value docs
100%
References docs
0%

Downloads

6.5K
CRAN downloads in the past year
Rank #7,525 · ~18/day · ~539/mo
Daily download trend is not available in this view yet.
18230 days
1.2K90 days
6.5K1 year
Compare downloads with other packages →
Also on101 r2u8 autocran

Dependencies

Declared dependencies
2 external dependencies (excludes base and recommended)
Depends (5)
methodsstatsrARPACKMatrixCompQuadForm
Imports (0)
none
LinkingTo (0)
none
Suggests (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (2)
Maintainer (1)
Author, Maintainer
Authors (2)
Author, Maintainer
Listed in earlier versions (2)
no longer listed · 1.4
no longer listed · 1.4
Package Timeline

4 releases. Pick two to compare their code metrics. R releases are shown for context.

  • R
    R 4.6.0 released · 2026-04-24
  • 1.4Latest
    2025-05-04 · current release · diff ↗
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • 1.3
    2023-10-01 · diff ↗
  • R
    R 4.3.0 released · 2023-04-21
  • 1.2
    2022-06-07 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • R
    R 4.0.0 released · 2020-04-24
  • R
    R 3.6.0 released · 2019-04-26
  • 1.1
    2019-03-05
  • R
    R 3.5.0 released · 2018-04-23

Package metadata

First published
2019-03-05
Total releases
4 / 7 yrs
License
GPL-2 OSI
Download size
11 KB
Installed size
not tracked yet
With dependencies
not tracked yet

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("POINT")
Holloway, S. T., & West, R. M. (2025). POINT: Protein Structure Guided Local Test (Version 1.4) [Computer software]. https://doi.org/10.32614/CRAN.package.POINT

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for POINT version 1.4 [Data set]. HJJB, LLC. Data release v2026-08-13. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-13, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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