Skip to content

PKNCA

Perform Pharmacokinetic Non-Compartmental Analysis

v0.12.1 · Aug 18, 2025 · AGPL-3

Description

Compute standard Non-Compartmental Analysis (NCA) parameters for typical pharmacokinetic analyses and summarize them.

Downloads

2.4K

Last 30 days

2672nd

7.8K

Last 90 days

42.7K

Last year

Trend: -8.1% (30d vs prior 30d)

CRAN Check Status

1 ERROR
12 OK
Show all 13 flavors
Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 ERROR
Check details (1 non-OK)
ERROR r-release-windows-x86_64

re-building of vignette outputs

Error(s) in re-building vignettes:
--- re-building 'v01-introduction-and-usage.Rmd' using rmarkdown
--- finished re-building 'v01-introduction-and-usage.Rmd'

--- re-building 'v02-example-theophylline.Rmd' using rmarkdown
--- finished re-building 'v02-example-theophylline.Rmd'

--- re-building 'v03-selection-of-calculation-intervals.Rmd' using rmarkdown
--- finished re-building 'v03-selection-of-calculation-intervals.Rmd'

--- re-building 'v04-sparse.Rmd' using rmarkdown
--- finished re-building 'v04-sparse.Rmd'

--- re-building 'v05-auc-calculation-with-PKNCA.Rmd' using rmarkdown
Loading required namespace: ggplot2
--- finished re-building 'v05-auc-calculation-with-PKNCA.Rmd'

--- re-building 'v06-half-life-calculation-tobit.Rmd' using rmarkdown
--- finished re-building 'v06-half-life-calculation-tobit.Rmd'

--- re-building 'v06-half-life-calculation.Rmd' using rmarkdown
--- finished re-building 'v06-half-life-calculation.Rmd'

--- re-building 'v07-post-processing.Rmd' using rmarkdown
...[truncated]...
inished re-building 'v21-methods-for-dose-aware-interpolation-and-extrapolation.Rmd'

--- re-building 'v22-time-to-steady-state.Rmd' using rmarkdown
--- finished re-building 'v22-time-to-steady-state.Rmd'

--- re-building 'v23-auc-integration-methods.Rmd' using rmarkdown
--- finished re-building 'v23-auc-integration-methods.Rmd'

+-+v23-auc-integration-methods.html
--- re-building 'v30-training-session.Rmd' using rmarkdown
--- finished re-building 'v30-training-session.Rmd'

--- re-building 'v40-options-for-controlling-PKNCA.Rmd' using rmarkdown
--- finished re-building 'v40-options-for-controlling-PKNCA.Rmd'

--- re-building 'v60-PKNCA-validation.Rmd' using rmarkdown
--- finished re-building 'v60-PKNCA-validation.Rmd'

--- re-building 'v80-writing-parameter-functions.Rmd' using rmarkdown
--- finished re-building 'v80-writing-parameter-functions.Rmd'

SUMMARY: processing the following file failed:
  'v23-auc-integration-methods.Rmd'

Error: Vignette re-building failed.
Execution halted

Check History

ERROR 12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Jun 27, 2026
ERROR r-release-windows-x86_64

re-building of vignette outputs

Error(s) in re-building vignettes:
--- re-building 'v01-introduction-and-usage.Rmd' using rmarkdown
--- finished re-building 'v01-introduction-and-usage.Rmd'

--- re-building 'v02-example-theophylline.Rmd' using rmarkdown
--- finished re-building 'v0
...[truncated]...
-writing-parameter-functions.Rmd' using rmarkdown
--- finished re-building 'v80-writing-parameter-functions.Rmd'

SUMMARY: processing the following file failed:
  'v23-auc-integration-methods.Rmd'

Error: Vignette re-building failed.
Execution halted
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Reverse Dependencies (5)

suggests

Dependency Network

Dependencies Reverse dependencies checkmate dplyr digest nlme purrr rlang tidyr tibble lifecycle aNCA pmxTools ruminate ubiquity babelmixr2 PKNCA

Version History

18 tracked
new 0.12.1 Mar 10, 2026
updated 0.12.1 ← 0.12.0 diff Aug 18, 2025
updated 0.12.0 ← 0.11.0 diff May 7, 2025
updated 0.11.0 ← 0.10.2 diff Jun 18, 2024
updated 0.10.2 ← 0.10.1 diff Apr 28, 2023
updated 0.10.1 ← 0.10.0 diff Jan 10, 2023
updated 0.10.0 ← 0.9.5 diff Oct 15, 2022
updated 0.9.5 ← 0.9.4 diff Oct 28, 2021
updated 0.9.4 ← 0.9.3 diff May 31, 2020
updated 0.9.3 ← 0.9.2 diff Apr 11, 2020
updated 0.9.2 ← 0.9.1 diff Feb 27, 2020
updated 0.9.1 ← 0.8.5 diff Jul 28, 2019
updated 0.8.5 ← 0.8.4 diff Jun 12, 2018
updated 0.8.4 ← 0.8.1 diff Jan 2, 2018
updated 0.8.1 ← 0.7.1 diff Dec 15, 2017