R Observatory: Metrics for PKNCA version 0.12.1

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

PKNCA

0.12.1

Perform Pharmacokinetic Non-Compartmental Analysis

5packages depend

41.3Kdownloads / year

99.0%test coverage

13/13checks pass

Overview

About

Maintained by Bill DenneyFirst published 2015-11-2217 releasesCRAN page ↗GitHub ↗

Compute standard Non-Compartmental Analysis (NCA) parameters for typical pharmacokinetic analyses and summarize them.

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("PKNCA", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("humanpred/pknca")

Development version from humanpred/pknca. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-pknca

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-PKNCA

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-PKNCA

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

13OK

Slowest check: 7.7 min · r-oldrel-windows-x86_64

Code health

Yes

Tests · ratio 1.04

99.0%

Coverage · measured lines

100%

Documentation · exports

11

Dependencies · direct

Check history

OK2026-08-05
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
NOTE2026-08-01
12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
OK2026-07-03
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-06-27
12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMEYes · 402 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo

Examples that run: 82%
Documented parameters: 97%
Return-value docs: 91%
References docs: 5%

Downloads

41.3K

CRAN downloads in the past year

Rank #2,579 · ~113/day · ~3.4K/mo

Releases R versions

Daily download trend is not available in this view yet.

2.4K30 days

7.3K90 days

41.3K1 year

Compare downloads with other packages →

Also on233 r2u12 autocran69 c2d4u

Repository

GitHub ↗ humanpred/pknca

86Stars

32Forks

51Open issues

16Open PRs

10Releases

1,295Commits

13Contributors

noncompartmental-analysiscranrncapharmacokinetics

License AGPL-3.0 · 1,295 commits · Last activity 2026-08-14 · +2.4% stars, 30d

Stars over time

2025-05-27 · 772026-08-14 · 86

Repository practices

Upstream repositoryBeta

4 development-tooling and community-health practices detected across 4 families in the upstream repository

Checks run against github.com/humanpred/pknca on 2026-08-09.

Continuous integration (1)

GitHub Actions

Reproducibility and dev environment (1)

data-raw/

Coverage (1)

Codecov

Governance and community (1)

Issue templates

How this is detected·Detection ruleset v1 (2026-07-18)

Development tooling

AI-assisted toolingBeta

Uses AI-assisted development tooling (declared in repo)

Earliest detected marker: claude on 2026-03-03

claude

Most recent: claude on 2026-03-03

Evidence

claude: on or before 2026-03-03 · evidence A, B, D · sole bot-author seen

How this is detected·Detection ruleset v2 (updated 2026-07-29)

Dependencies

Declared dependencies

20 external dependencies (excludes base and recommended)

Depends (0)

none

Imports (11)

checkmate dplyr digestnlmepurrr rlangstatstidyr tibbleutilslifecycle

LinkingTo (0)

none

Suggests (12)

covr cowplot ggplot2 knitr labeling pander pmxTools rmarkdown spelling testthat units withr

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

5direct

0indirect

aNCA pmxTools ruminate ubiquity babelmixr2

Code & Tests

People & History

People (4)

Maintainer (1)

Bill Denney

Author, Maintainer

Authors (3)

Bill Denney

Author, Maintainer

Clare Buckeridge

Author

Gerardo Jose Rodriguez

Author · added in 0.12.1

Contributors (1)

Sridhar Duvvuri

Contributor · added in 0.7.1

Package Timeline

17 releases. Pick two to compare their code metrics. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
0.12.1Latest
2025-08-19 · current release · diff ↗
0.12.0
2025-05-08 · diff ↗
R
R 4.5.0 released · 2025-04-11
0.11.0
2024-06-19 · diff ↗
R
R 4.4.0 released · 2024-04-24
0.10.2
2023-04-29 · diff ↗
R
R 4.3.0 released · 2023-04-21
0.10.1
2023-01-11 · diff ↗
0.10.0
2022-10-16 · diff ↗
R
R 4.2.0 released · 2022-04-22
0.9.5
2021-10-29 · diff ↗
R
R 4.1.0 released · 2021-05-18
0.9.4
2020-06-01 · diff ↗
R
R 4.0.0 released · 2020-04-24
0.9.3
2020-04-12 · diff ↗

Show 15 earlier events

0.9.2
2020-02-28 · diff ↗
0.9.1
2019-07-29 · diff ↗
R
R 3.6.0 released · 2019-04-26
0.8.5
2018-06-13 · diff ↗
R
R 3.5.0 released · 2018-04-23
0.8.4
2018-01-03 · diff ↗
unarchivedReturned to CRAN
2018-01-03
0.8.1
2017-12-16 · diff ↗
orphanedOrphaned by its maintainer
2017-12-16
there was no response to requests for needed corrections
R
R 3.4.0 released · 2017-04-21
0.7.1
2016-08-15 · diff ↗
R
R 3.3.0 released · 2016-05-03
0.7
2016-04-01 · diff ↗
0.6
2015-11-22
R
R 3.2.0 released · 2015-04-16

Package metadata

First published: 2015-11-22
Total releases: 17 / 11 yrs
License: AGPL-3 OSI
Download size: 1.0 MB
Installed size: not tracked yet
With dependencies: not tracked yet

Appears in task views

Mixed, Multilevel, and Hierarchical Models in R Analysis of Pharmacokinetic Data

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("PKNCA")

Format

Denney, B., Buckeridge, C., Duvvuri, S., & Rodriguez, G. J. (2025). PKNCA: Perform Pharmacokinetic Non-Compartmental Analysis (Version 0.12.1) [Computer software]. https://doi.org/10.32614/CRAN.package.PKNCA

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for PKNCA version 0.12.1 [Data set]. HJJB, LLC. Data release v2026-08-15. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-15, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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