Cluster Gauss-Newton Method
Overview
Find multiple solutions of a nonlinear least squares problem. Cluster Gauss-Newton method does not assume uniqueness of the solution of the nonlinear least squares problem and compute multiple minimizers. Please cite the following paper when this software is used in your research: Aoki et al. (2020) doi:10.1007/s11081-020-09571-2. Cluster Gauss–Newton method. Optimization and Engineering, 1-31. Please cite the following paper when profile likelihood plot is drawn with this software and used in your research: Aoki and Sugiyama (2024) doi:10.1002/psp4.13055. Cluster Gauss-Newton method for a quick approximation of profile likelihood: With application to physiologically-based pharmacokinetic models. CPT Pharmacometrics Syst Pharmacol.13(1):54-67. GPT based helper bot available at https://chatgpt.com/g/g-684936db9e748191a2796debb00cd755-cluster-gauss-newton-method-helper-bot .
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK14 OK2026-03-10
Documentation
- Help pages
- 36 (1 internal)includes a package overview page
- Examples that run
- 68%23 run in a plain check · 11 never run
- Exported functions with examples
- 100%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 3%
Downloads
Dependencies
Code & Tests
People & History
Pick two releases to compare their code metrics.
- 0.10.0Latest2026-09-13 · current release · diff ↗ ·
added 5 exports
as_CGNM_result_S4, generateCGNM_script, make_ShinyCGNM_initialCondition, make_ShinyCGNM_parameterInfo, make_ShinyCGNM_simulationTimepoints - RR 4.6.0 released · 2026-04-24
- 0.9.32026-01-08 · diff ↗
- 0.9.2
- RR 4.5.0 released · 2025-04-11
- 0.9.12025-01-28 · diff ↗ ·
added 3 exports
Cluster_Gauss_Newton_EBE_method, make_ShinyCGNM_doseData, make_ShinyCGNM_observationData - 0.9.02024-06-12 · diff ↗
- RR 4.4.0 released · 2024-04-24
- 0.8.0
- 0.6.72024-01-18 · diff ↗
- 0.6.52023-05-19 · diff ↗ ·
added 4 exports
plot_simulationMatrixWithCI, plot_simulationWithCI, suggestInitialLowerRange, suggestInitialUpperRange - RR 4.3.0 released · 2023-04-21
- 0.6.2
- unarchivedReturned to CRAN2022-11-01
- 0.5.1
- archivedRemoved from CRAN2022-10-24issues were not corrected in time
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- 0.4.0
- 0.3.22022-06-04 · diff ↗ ·
removed 2 exports
acceptedIndecies, acceptedIndecies_binaryadded 6 exports
acceptedIndices, acceptedIndices_binary, plot_goodnessOfFit, plot_paraDistribution_byHistogram, table_parameterSummary, topIndices - RR 4.2.0 released · 2022-04-22
- 0.3.12022-03-14 · diff ↗ ·
added 4 exports
Cluster_Gauss_Newton_Bootstrap_method, bestApproximateMinimizers, plot_SSR_parameterValue, plot_parameterValue_scatterPlots - 0.1.12022-01-10 · diff ↗
- 0.1.02022-01-06
- RR 4.1.0 released · 2021-05-18
Package metadata
- First published
- 2022-01-06
- Total releases
- 15 / 4 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 3.5.0
- Download size
- 374 KB
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