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BRINDA

0.1.5Package record

Computation of BRINDA Adjusted Micronutrient Biomarkers for Inflammation

0packages depend
3.6Kdownloads / year
0.0%test coverage
13/13flavors OK

Overview

About

Inflammation can affect many micronutrient biomarkers and can thus lead to incorrect diagnosis of individuals and to over- or under-estimate the prevalence of deficiency in a population. Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) is a multi-agency and multi-country partnership designed to improve the interpretation of nutrient biomarkers in settings of inflammation and to generate context-specific estimates of risk factors for anemia (Suchdev (2016) doi:10.3945/an.115.010215). In the past few years, BRINDA published a series of papers to provide guidance on how to adjust micronutrient biomarkers, retinol binding protein, serum retinol, serum ferritin by Namaste (2020), soluble transferrin receptor (sTfR), serum zinc, serum and Red Blood Cell (RBC) folate, and serum B-12, using inflammation markers, alpha-1-acid glycoprotein (AGP) and/or C-Reactive Protein (CRP) by Namaste (2020) doi:10.1093/ajcn/nqaa141, Rohner (2017) doi:10.3945/ajcn.116.142232, McDonald (2020) doi:10.1093/ajcn/nqz304, and Young (2020) doi:10.1093/ajcn/nqz303. The BRINDA inflammation adjustment method mainly focuses on Women of Reproductive Age (WRA) and Preschool-age Children (PSC); however, the general principle of the BRINDA method might apply to other population groups. The BRINDA R package is a user-friendly all-in-one R package that uses a series of functions to implement BRINDA adjustment method, as described above. The BRINDA R package will first carry out rigorous checks and provides users guidance to correct data or input errors (if they occur) prior to inflammation adjustments. After no errors are detected, the package implements the BRINDA inflammation adjustment for up to five micronutrient biomarkers, namely retinol-binding-protein, serum retinol, serum ferritin, sTfR, and serum zinc (when appropriate), using inflammation indicators of AGP and/or CRP for various population groups. Of note, adjustment for serum and RBC folate and serum B-12 is not included in the R package, since evidence shows that no adjustment is needed for these micronutrient biomarkers in either WRA or PSC groups (Young (2020) doi:10.1093/ajcn/nqz303).

Changes in 0.1.5
  • Change the condition of adjusting for sTfR. sTfR is adjusted by AGP only in WRA and PSC population groups. sTfR can be adjusted by AGP or CRP in other/manual population groups.
  • 10/16/2022:moved URL: https://brinda-nutrition.org/publications/ to

https://www.brinda-nutrition.org/publications)

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 1.8 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-06-09
  • ERROR12 OK, 1 ERROR2026-06-08
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 0.1.5
READMEYes · 211 wordsVignettesNoNEWSYes · 67% structured · mentions 0.1.5Citation fileNoWebsitenot declared in DESCRIPTION
Help pages
2
Examples that run
100%1 run in a plain check
Exported functions with examples
100%
Documented parameters
100%
Return-value docs
100%
Help pages citing references
50%

Downloads

3.6K
CRAN downloads in the past year
Rank #11,632 · ~10/day · ~301/mo
Daily download trend is not available in this view yet.
33630 days
93590 days
3.6K1 year
Compare downloads with other packages →
Also on98 r2u6 autocran37 c2d4u

Repository

3Stars
0Forks
0Open issues
0Open PRs
1Releases
35Commits
2Commit identities
License file reads as CC-BY-4.0 · 35 commits · Last activity 2022-10-16
Responsiveness
not measured

Stars over time

2024-12-19 · 32026-07-07 · 3
PracticesBeta

6 development-tooling and community-health practices detected across 4 families in the upstream repository

Checks run against github.com/hanqiluo/brinda on 2026-10-21.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (1)
README.Rmd
CRAN release process (2)
cran-comments.mdCRAN-SUBMISSION
Lint, format, editor (1)
RStudio project
How this is detected·Detection ruleset v4 (2026-10-20)

Dependencies

Declared dependencies
6 external dependencies (excludes base and recommended)

Installing BRINDA adds 60 packages (30 with compiled code, 55 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, data.table 5.7 MB.

Depends (1)
R >= 4.1.0
LinkingTo (0)
none
Suggests (1)
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (3)
Maintainer since 0.1.3 (2021), Author
Author
Contributor · added in 0.1.5
Listed in earlier versions (1)
Afrin Jahan
no longer listed · 0.1.3 to 0.1.4
Releases (3)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • R
    R 4.3.0 released · 2023-04-21
  • 0.1.5Latest
    record
    2022-10-16 · current release · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • 0.1.4
    record
    2022-04-12 · diff ↗
  • 0.1.3
    record
    2021-11-10
  • R
    R 4.1.0 released · 2021-05-18

Package metadata

First published
2021-11-10
Total releases
3 / 5 yrs
License
CC BY 4.0
Minimum R
≥ 4.1.0
Bundled data
2.3 KB / 1 file
Download size
16 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("BRINDA")
Luo, H., Addo, O. Y., & Geng, J. (2022). BRINDA: Computation of BRINDA Adjusted Micronutrient Biomarkers for Inflammation (Version 0.1.5) [Computer software]. https://doi.org/10.32614/CRAN.package.BRINDA

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for BRINDA version 0.1.5 [Data set]. HJJB, LLC. Data release v2026-10-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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