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synlet

Bioc current

Hits Selection for Synthetic Lethal RNAi Screen Data

v2.12.0 · software · GPL-3

Release Lineage

Entered 3.2 · Oct 14, 2015

Current · Requires R 4.6

1.0 In 22 of 49 releases 3.23

Description

Select hits from synthetic lethal RNAi screen data. For example, there are two identical celllines except one gene is knocked-down in one cellline. The interest is to find genes that lead to stronger lethal effect when they are knocked-down further by siRNA. Quality control and various visualisation tools are implemented. Four different algorithms could be used to pick up the interesting hits. This package is designed based on 384 wells plates, but may apply to other platforms with proper configuration.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

20 9 exported

Complexity

2.5 avg / 8 max

Call network

20 nodes / 7 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

1,519

Files

32

Compiled share

0%

Has compiled src

No

Language breakdown

R 842 (55.4%)Tests 29 (1.9%)Docs 423 (27.8%)Vignettes 225 (14.8%)

API

Exported functions

9

Internal functions

11

Testing & CI

Has tests

Yes

Test-to-code ratio

0.03

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

System requirements

C++ standard

License

GPL-3

License flags

SPDX valid, OSI approved

History

Versions

22

First release

2015-10-13

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

Dep drift

10

LOC over versions

v3.2: 1,527 LOCv3.3: 1,527 LOCv3.4: 1,527 LOCv3.5: 1,527 LOCv3.6: 1,527 LOCv3.7: 1,527 LOCv3.8: 1,527 LOCv3.9: 1,527 LOCv3.10: 1,527 LOCv3.11: 1,527 LOCv3.12: 1,527 LOCv3.13: 1,527 LOCv3.14: 1,527 LOCv3.15: 1,527 LOCv3.16: 1,527 LOCv3.17: 1,519 LOCv3.18: 1,519 LOCv3.19: 1,519 LOCv3.20: 1,519 LOCv3.21: 1,519 LOCv3.22: 1,519 LOCv3.23: 1,519 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMENoVignettesYes · dynamicpkgdown siteNoNEWSYes · 67% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
99%
Return-value docs
100%
References docs
60%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("synlet")
Shao, C. (2026). synlet: Hits Selection for Synthetic Lethal RNAi Screen Data (Version 2.12.0) [Computer software]. https://bioconductor.org/packages/synlet

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for synlet version 2.12.0 [Data set]. HJJB, LLC. Data release v2026-08-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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